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    Sectm1a secreted and transmembrane 1A [ Mus musculus (house mouse) ]

    Gene ID: 209588, updated on 27-Nov-2024

    Summary

    Official Symbol
    Sectm1aprovided by MGI
    Official Full Name
    secreted and transmembrane 1Aprovided by MGI
    Primary source
    MGI:MGI:2384805
    See related
    Ensembl:ENSMUSG00000025165 AllianceGenome:MGI:2384805
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable cytokine activity. Predicted to be involved in immune response and signal transduction. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in membrane. Is expressed in cortical plate. Orthologous to human SECTM1 (secreted and transmembrane 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in testis adult (RPKM 2.8), colon adult (RPKM 2.3) and 17 other tissues See more
    NEW
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    Genomic context

    See Sectm1a in Genome Data Viewer
    Location:
    11 E2; 11 84.89 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120958221..120988023, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (121067395..121097153, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11775 Neighboring gene CD7 antigen Neighboring gene secreted and transmembrane 1B Neighboring gene predicted gene 11793 Neighboring gene testis expressed gene 19.2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1)  1 citation
    • Targeted (1) 

    General gene information

    Clone Names

    • MGC7970

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    secreted and transmembrane protein 1A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145373.2NP_663348.2  secreted and transmembrane protein 1A precursor

      See identical proteins and their annotated locations for NP_663348.2

      Status: VALIDATED

      Source sequence(s)
      AK082020, AL662887, AW985540
      Consensus CDS
      CCDS25766.1
      UniProtKB/Swiss-Prot
      Q921W8
      UniProtKB/TrEMBL
      A2ABP9
      Related
      ENSMUSP00000026162.6, ENSMUST00000026162.12

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      120958221..120988023 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532748.5XP_006532811.1  secreted and transmembrane protein 1A isoform X1

      See identical proteins and their annotated locations for XP_006532811.1

      UniProtKB/Swiss-Prot
      Q921W8
      UniProtKB/TrEMBL
      A2ABP9
    2. XM_017314413.1XP_017169902.1  secreted and transmembrane protein 1A isoform X1

      UniProtKB/Swiss-Prot
      Q921W8
      UniProtKB/TrEMBL
      A2ABP9
    3. XM_036156494.1XP_036012387.1  secreted and transmembrane protein 1A isoform X2

      UniProtKB/Swiss-Prot
      Q921W8
      UniProtKB/TrEMBL
      A2ABP7
      Related
      ENSMUSP00000101726.3, ENSMUST00000106120.3
    4. XM_017314414.1XP_017169903.1  secreted and transmembrane protein 1A isoform X3