Tom20 Translocase of outer membrane 20 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Tom20provided by FlyBase
Official Full Name: Translocase of outer membrane 20provided by FlyBase
Primary source: FLYBASE:FBgn0036928
Locus tag: Dmel_CG7654
See related: AllianceGenome:FB:FBgn0036928
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.225; CG7654; Dmel\CG7654; dtom20; TOM 20; tom20; TOM20
Summary: Predicted to enable mitochondrion targeting sequence binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and tRNA import into mitochondrion. Located in mitochondrion. Part of mitochondrial outer membrane translocase complex. Is active in mitochondrial outer membrane. Is expressed in several structures, including Malpighian tubule primordium; embryonic/larval midgut primordium; gut section; larval muscle cell; and mesoderm. Orthologous to human TOMM20 (translocase of outer mitochondrial membrane 20). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (20000644..20002446)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (19993744..19995546)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster.
Title: Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables mitochondrion targeting sequence binding	IBA Inferred from Biological aspect of Ancestor more info
contributes_to protein transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to protein transmembrane transporter activity	IC Inferred by Curator more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein targeting	IEA Inferred from Electronic Annotation more info
involved_in protein targeting to mitochondrion	IC Inferred by Curator more info	PubMed
involved_in tRNA import into mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrial outer membrane	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial outer membrane translocase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial outer membrane translocase complex	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial outer membrane translocase complex	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain