Mfsd3 major facilitator superfamily domain containing 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mfsd3provided by MGI
Official Full Name: major facilitator superfamily domain containing 3provided by MGI
Primary source: MGI:MGI:1916822
See related: Ensembl:ENSMUSG00000019080 AllianceGenome:MGI:1916822
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2310010G13Rik
Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Orthologous to human MFSD3 (major facilitator superfamily domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in adrenal adult (RPKM 19.7), mammary gland adult (RPKM 12.3) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 D3; 15 36.28 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (76585742..76588439)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (76701542..76704239)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Protein expression of MFSD3 is in mouse brain regions is specifically affected by altered nutrient uptake.
Title: The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: major facilitator superfamily domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027122.3 → NP_081398.2 major facilitator superfamily domain-containing protein 3

See identical proteins and their annotated locations for NP_081398.2

Status: PROVISIONAL

Source sequence(s)

AK089539

Consensus CDS

CCDS27587.1

UniProtKB/Swiss-Prot

Q5U419, Q8VED1, Q9D7F8

UniProtKB/TrEMBL

A0A0R4J004

Related

ENSMUSP00000019224.8, ENSMUST00000019224.9

Conserved Domains (1) summary

cl21472
Location:8 → 402

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...