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    Tapdelta Translocon-associated protein delta [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 45680, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tapdeltaprovided by FlyBase
    Official Full Name
    Translocon-associated protein deltaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0021795
    Locus tag
    Dmel_CG9035
    See related
    AllianceGenome:FB:FBgn0021795
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM12291; CG9035; delta; Dmel\CG9035; l(2)k17005; TRAPdelta
    Summary
    Located in endomembrane system. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; gut section; mesoderm; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iy. Orthologous to human SSR4 (signal sequence receptor subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tapdelta in Genome Data Viewer
    Location:
    47F7-47F7; 2-64 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11370300..11371335, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7257805..7258840, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 47b Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Tetraspanin 47F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor. Ben SB, et al. Biochemistry (Mosc), 2011 Sep. PMID 22082272
    2. Inhibition of Daughterless by Extramacrochaetae mediates Notch-induced cell proliferation. Spratford CM, et al. Development, 2015 Jun 1. PMID 25977368, Free PMC Article
    3. CrebA regulates secretory activity in the Drosophila salivary gland and epidermis. Abrams EW, et al. Development, 2005 Jun. PMID 15901661
    4. Characterization of the Drosophila lipid droplet subproteome. Beller M, et al. Mol Cell Proteomics, 2006 Jun. PMID 16543254
    5. A targeted gain-of-function screen identifies genes affecting salivary gland morphogenesis/tubulogenesis in Drosophila. Maybeck V, et al. Genetics, 2009 Feb. PMID 19064711, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Translocon-associated protein delta
    Names
    CG9035-PA
    CG9035-PB
    Tapdelta-PA
    Tapdelta-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11370300..11371335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299386.1 → NP_001286315.1  Translocon-associated protein delta, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286315.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KLX3
      Conserved Domains (1) summary
      pfam05404
      Location:5 → 165
      TRAP-delta; Translocon-associated protein, delta subunit precursor (TRAP-delta)

    2. NM_136835.4 → NP_610679.1  Translocon-associated protein delta, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610679.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KLX3
      Related
      FBpp0087250
      Conserved Domains (1) summary
      pfam05404
      Location:5 → 165
      TRAP-delta; Translocon-associated protein, delta subunit precursor (TRAP-delta)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KLX3 Q7KLX3

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