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    RUFY3 RUN and FYVE domain containing 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 514798, updated on 30-Jan-2025

    Summary

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    Official Symbol
    RUFY3provided by VGNC
    Official Full Name
    RUN and FYVE domain containing 3provided by VGNC
    Primary source
    VGNC:VGNC:34215
    See related
    BGD:BT28037; EnsemblRapid:ENSBTAG00070003460
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RUFY3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (86092771..86184499)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene joining chain of multimeric IgA and IgM Neighboring gene UTP3 small subunit processome component Neighboring gene uncharacterized LOC112447097 Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene G-rich RNA sequence binding factor 1 Neighboring gene MOB kinase activator 1B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein RUFY3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191522.1 → NP_001178451.1  protein RUFY3

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000006
      UniProtKB/TrEMBL
      E1BNY5
      Conserved Domains (4) summary
      pfam01442
      Location:332 → 504
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      pfam02759
      Location:161 → 284
      RUN; RUN domain
      pfam10212
      Location:331 → 380
      TTKRSYEDQ; Predicted coiled-coil domain-containing protein
      cl23720
      Location:398 → 504
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      86092771..86184499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010806206.4 → XP_010804508.1  protein RUFY3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SSG8, A0AAA9T5Y4
      Conserved Domains (4) summary
      cd15744
      Location:627 → 673
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:161 → 282
      RUN; RUN domain
      cl25732
      Location:301 → 593
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27544
      Location:5 → 100
      Herpes_glycop_D; Herpesvirus glycoprotein D/GG/GX domain

    2. XM_059887490.1 → XP_059743473.1  protein RUFY3 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SU19, E1BNY5

    3. XM_010806208.4 → XP_010804510.1  protein RUFY3 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SSG8
      Conserved Domains (4) summary
      cd15744
      Location:622 → 668
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:161 → 282
      RUN; RUN domain
      cl25732
      Location:301 → 593
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27544
      Location:5 → 100
      Herpes_glycop_D; Herpesvirus glycoprotein D/GG/GX domain

    4. XM_059887491.1 → XP_059743474.1  protein RUFY3 isoform X5

      UniProtKB/TrEMBL
      E1BNY5
      Related
      ENSBTAP00070004558.1, ENSBTAT00070007916.1

    5. XM_059887492.1 → XP_059743475.1  protein RUFY3 isoform X6

      UniProtKB/TrEMBL
      A0AAA9U064

    6. XM_059887498.1 → XP_059743481.1  protein RUFY3 isoform X12

      UniProtKB/TrEMBL
      E1BNY5

    7. XM_059887500.1 → XP_059743483.1  protein RUFY3 isoform X14

      UniProtKB/TrEMBL
      A0AAA9U064

    8. XM_059887489.1 → XP_059743472.1  protein RUFY3 isoform X3

      UniProtKB/TrEMBL
      A0AAA9SSG8
      Related
      ENSBTAP00070004563.1, ENSBTAT00070007922.1

    9. XM_059887495.1 → XP_059743478.1  protein RUFY3 isoform X9

      UniProtKB/TrEMBL
      A0AAA9U064

    10. XM_059887494.1 → XP_059743477.1  protein RUFY3 isoform X8

      UniProtKB/TrEMBL
      E1BNY5

    11. XM_059887497.1 → XP_059743480.1  protein RUFY3 isoform X11

      UniProtKB/TrEMBL
      E1BNY5
      Related
      ENSBTAP00070004548.1, ENSBTAT00070007900.1

    12. XM_059887502.1 → XP_059743485.1  protein RUFY3 isoform X16

      UniProtKB/TrEMBL
      A0AAA9U064

    13. XM_059887501.1 → XP_059743484.1  protein RUFY3 isoform X15

      UniProtKB/TrEMBL
      E1BNY5

    14. XM_059887499.1 → XP_059743482.1  protein RUFY3 isoform X13

      UniProtKB/TrEMBL
      E1BNY5

    15. XM_024993198.2 → XP_024848966.1  protein RUFY3 isoform X17

      UniProtKB/TrEMBL
      A0AAA9T4R7, E1BNY5
      Related
      ENSBTAP00070004546.1, ENSBTAT00070007896.1
      Conserved Domains (3) summary
      COG1196
      Location:316 → 522
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:161 → 282
      RUN; RUN domain
      cl27544
      Location:5 → 100
      Herpes_glycop_D; Herpesvirus glycoprotein D/GG/GX domain

    16. XM_059887493.1 → XP_059743476.1  protein RUFY3 isoform X7

      UniProtKB/TrEMBL
      A0AAA9TWI7

    17. XM_059887496.1 → XP_059743479.1  protein RUFY3 isoform X10

      UniProtKB/TrEMBL
      A0AAA9S8Y9, A0AAA9TWI7
      Related
      ENSBTAP00070004542.1, ENSBTAT00070007886.1

    18. XM_059887503.1 → XP_059743486.1  protein RUFY3 isoform X18

      UniProtKB/TrEMBL
      A0AAA9RWI2

    19. XM_005208087.5 → XP_005208144.1  protein RUFY3 isoform X19

      UniProtKB/TrEMBL
      A0AAA9RWI2
      Conserved Domains (2) summary
      COG1196
      Location:258 → 464
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    RNA

    1. XR_009494770.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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