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    fs(1)K10 female sterile (1) K10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 47781, updated on 17-Dec-2024

    Summary

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    Official Symbol
    fs(1)K10provided by FlyBase
    Official Full Name
    female sterile (1) K10provided by FlyBase
    Primary source
    FLYBASE:FBgn0000810
    Locus tag
    Dmel_CG3218
    See related
    AllianceGenome:FB:FBgn0000810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3218; Dmel\CG3218; EG:30B8.5; f(s)K10; fs(1)k10; fs(1)M9; K-10; k10; K10
    Summary
    Predicted to enable DNA binding activity. Involved in follicle cell of egg chamber development and pole plasm mRNA localization. Located in nucleus. Is expressed in several structures, including egg chamber; female germline cell; germarium; and ovary. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fs(1)K10 in Genome Data Viewer
    Location:
    2F1-2F2; 1-0.9 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2242138..2246041)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2136171..2140074)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pecanex Neighboring gene kurz Neighboring gene Odorant receptor 2a Neighboring gene crooked neck

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The development and function of the female germ line in Drosophila melanogaster: a cell lineage study. Wieschaus E, et al. Dev Biol, 1979 Jan. PMID 108155
    2. Role of the oocyte nucleus in determination of the dorsoventral polarity of Drosophila as revealed by molecular analysis of the K10 gene. Prost E, et al. Genes Dev, 1988 Jul. PMID 12553295
    3. A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA. Serano TL, et al. Development, 1995 Nov. PMID 8582290
    4. Solution structure of the DNA binding octapeptide repeat of the K10 gene product. Suzuki M, et al. Protein Eng, 1994 Apr. PMID 8029203
    5. fs(1)K10, a germline-dependent female sterile mutation causing abnormal chorion morphology inDrosophila melanogaster. Wieschaus E, et al. Wilehm Roux Arch Dev Biol, 1978 Mar. PMID 28305014

    See all (179) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dorsal/ventral pattern formation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in follicle cell of egg chamber development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular mRNA localization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pole plasm mRNA localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    female sterile (1) K10
    Names
    CG3218-PA
    fs(1)K10-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2242138..2246041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058143.4 → NP_477491.1  female sterile (1) K10 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477491.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O46075, P13468, Q9W505
      Related
      FBpp0070380
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P13468.2 P13468

    Gene LinkOut

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