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    NK7.1 NK7.1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41747, updated on 4-Jan-2025

    Summary

    Official Symbol
    NK7.1provided by FlyBase
    Official Full Name
    NK7.1provided by FlyBase
    Primary source
    FLYBASE:FBgn0024321
    Locus tag
    Dmel_CG8524
    See related
    AllianceGenome:FB:FBgn0024321
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8524; Dmel\CG8524; NK-7.1; NK7
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including cephalic vascular rudiment; embryonic/larval midgut primordium; embryonic/larval posterior spiracle; gland; and gut section. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See NK7.1 in Genome Data Viewer
    Location:
    88B4-88B6; 3-55 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14329413..14372951, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10155135..10198673, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene SET domain containing 8 Neighboring gene Aftiphilin Neighboring gene ATP synthase, subunit E Neighboring gene spindle B Neighboring gene Dynein axonemal assembly factor 5 Neighboring gene long non-coding RNA:CR44943 Neighboring gene scotti

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cell differentiation  
    involved_in regulation of DNA-templated transcription  
    involved_in regulation of transcription by RNA polymerase II  
    Component Evidence Code Pubs
    is_active_in nucleus  

    General protein information

    Preferred Names
    NK7.1
    Names
    CG8524-PA
    CG8524-PB
    CG8524-PC
    CG8524-PD
    Dm.HboxNK-7.1
    NK7.1-PA
    NK7.1-PB
    NK7.1-PC
    NK7.1-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14329413..14372951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260174.3 → NP_001247103.1  NK7.1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247103.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W347, Q9VFK4
      Conserved Domains (1) summary
      pfam00046
      Location:397 → 449
      Homeobox; Homeobox domain
    2. NM_142100.3 → NP_650357.2  NK7.1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650357.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W347, Q9VFK4
      Related
      FBpp0082400
      Conserved Domains (1) summary
      pfam00046
      Location:397 → 449
      Homeobox; Homeobox domain
    3. NM_001316524.1 → NP_001303453.1  NK7.1, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W347, Q9VFK4
      Conserved Domains (1) summary
      pfam00046
      Location:397 → 449
      Homeobox; Homeobox domain
    4. NM_169580.3 → NP_731904.1  NK7.1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731904.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W347, Q9VFK4
      Related
      FBpp0082401
      Conserved Domains (1) summary
      pfam00046
      Location:397 → 449
      Homeobox; Homeobox domain
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