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    ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [ Bos taurus (domestic cattle) ]

    Gene ID: 444860, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ST3GAL6provided by VGNC
    Official Full Name
    ST3 beta-galactoside alpha-2,3-sialyltransferase 6provided by VGNC
    Primary source
    VGNC:VGNC:35335
    See related
    BGD:BT11756; Ensembl:ENSBTAG00000004471
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    SIAT10
    Orthologs
    human mouse all
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    Genomic context

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    See ST3GAL6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (42985053..43111608)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100848540 Neighboring gene small nucleolar RNA SNORA68 Neighboring gene coproporphyrinogen oxidase Neighboring gene uncharacterized LOC104970815 Neighboring gene discoidin, CUB and LCCL domain containing 2 Neighboring gene transfer RNA glutamic acid (anticodon UUC)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta-galactoside alpha-2,3-sialyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycolipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type 2 lactosamine alpha-2,3-sialyltransferase
    Names
    CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI
    ST3Gal VI
    ST3GalVI
    sialyltransferase 10
    sialyltransferase ST3Gal-VI
    NP_001002883.1
    XP_024851622.1
    XP_059745558.1
    XP_059745566.1
    XP_059745567.1
    XP_059745574.1
    XP_059745596.1
    XP_059745623.1
    XP_059745643.1
    XP_059745682.1
    XP_059745711.1
    XP_059745743.1
    XP_059745780.1
    XP_059745811.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002883.2 → NP_001002883.1  type 2 lactosamine alpha-2,3-sialyltransferase

      See identical proteins and their annotated locations for NP_001002883.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133294
      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5
      Related
      ENSBTAP00000005868.3, ENSBTAT00000005868.4
      Conserved Domains (1) summary
      pfam00777
      Location:61 → 329
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42985053..43111608
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059889591.1 → XP_059745574.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    2. XM_059889575.1 → XP_059745558.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    3. XM_059889640.1 → XP_059745623.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    4. XM_059889760.1 → XP_059745743.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LVL5, A0AAF6ZZ52
      Related
      ENSBTAP00000059813.2, ENSBTAT00000069771.2

    5. XM_059889728.1 → XP_059745711.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    6. XM_059889699.1 → XP_059745682.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    7. XM_024995854.2 → XP_024851622.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X3

      Conserved Domains (1) summary
      pfam00777
      Location:61 → 235
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    8. XM_059889583.1 → XP_059745566.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    9. XM_059889584.1 → XP_059745567.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    10. XM_059889613.1 → XP_059745596.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    11. XM_059889660.1 → XP_059745643.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q6H8M7
      UniProtKB/TrEMBL
      A0A3Q1LVL5

    12. XM_059889828.1 → XP_059745811.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X5

    13. XM_059889797.1 → XP_059745780.1  type 2 lactosamine alpha-2,3-sialyltransferase isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6H8M7.1 GenPept UniProtKB/Swiss-Prot:Q6H8M7

    Gene LinkOut

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