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    AP2M1 adaptor related protein complex 2 subunit mu 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 517446, updated on 27-Dec-2024

    Summary

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    Official Symbol
    AP2M1provided by VGNC
    Official Full Name
    adaptor related protein complex 2 subunit mu 1provided by VGNC
    Primary source
    VGNC:VGNC:25985
    See related
    BGD:BT11080; Ensembl:ENSBTAG00000020106
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See AP2M1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (82968891..82979160, complement)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-1224 Neighboring gene von Willebrand factor A domain containing 5B2 Neighboring gene ATP binding cassette subfamily F member 3 Neighboring gene uncharacterized LOC101907353 Neighboring gene dishevelled segment polarity protein 3 Neighboring gene eukaryotic translation initiation factor 2B subunit epsilon

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128246

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables clathrin adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in clathrin-dependent endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of AP-2 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AP-2 complex subunit mu
    Names
    AP-2 mu chain
    HA2 50 kDa subunit
    adapter-related protein complex 2 mu subunit
    adapter-related protein complex 2 subunit mu
    adaptor protein complex AP-2 subunit mu
    adaptor related protein complex 2 mu 1 subunit
    adaptor-related protein complex 2 subunit mu
    clathrin assembly protein complex 2 medium chain
    clathrin assembly protein complex 2 mu medium chain
    clathrin coat assembly protein AP50
    clathrin coat-associated protein AP50
    mu2-adaptin
    plasma membrane adaptor AP-2 50 kDa protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034523.2 → NP_001029695.1  AP-2 complex subunit mu

      See identical proteins and their annotated locations for NP_001029695.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102983
      UniProtKB/Swiss-Prot
      Q3ZC13
      Related
      ENSBTAP00000068539.1, ENSBTAT00000071273.2
      Conserved Domains (2) summary
      cd09251
      Location:168 → 434
      AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
      cd14836
      Location:1 → 140
      AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      82968891..82979160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005201594.4 → XP_005201651.1  AP-2 complex subunit mu isoform X1

      See identical proteins and their annotated locations for XP_005201651.1

      Conserved Domains (2) summary
      cd09251
      Location:166 → 432
      AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
      cd14836
      Location:1 → 140
      AP2_Mu_N; AP-2 complex subunit mu N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ZC13.1 GenPept UniProtKB/Swiss-Prot:Q3ZC13

    Gene LinkOut

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