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    ACADVL acyl-CoA dehydrogenase very long chain [ Bos taurus (domestic cattle) ]

    Gene ID: 282130, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ACADVLprovided by VGNC
    Official Full Name
    acyl-CoA dehydrogenase very long chainprovided by VGNC
    Primary source
    VGNC:VGNC:50246
    See related
    BGD:BT10853; Ensembl:ENSBTAG00000003072
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ACADVL in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (26934843..26940041)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA1 Neighboring gene discs large MAGUK scaffold protein 4 Neighboring gene microRNA mir-324 Neighboring gene dishevelled segment polarity protein 2 Neighboring gene PHD finger protein 23

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR) rapidly identified a critical missense mutation (P236T) of bovine ACADVL gene affecting growth traits. Zhang S, et al. Gene, 2015 Apr 1. PMID 25620159
    2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Bovine ACADVL gene had a significant effect on chest width (P<0.05), chest depth (P<0.05), and hip width (P<0.05) in the Qinchuan breed.
      Title: Tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR) rapidly identified a critical missense mutation (P236T) of bovine ACADVL gene affecting growth traits.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables very-long-chain fatty acyl-CoA dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    very long-chain specific acyl-CoA dehydrogenase, mitochondrial
    Names
    VLCAD
    acyl-coenzyme A dehydrogenase, very long chain
    NP_776919.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174494.2 → NP_776919.1  very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_776919.1

      Status: PROVISIONAL

      Source sequence(s)
      U30817
      UniProtKB/TrEMBL
      A0AAA9T914
      Related
      ENSBTAP00000092384.1, ENSBTAT00000124426.1
      Conserved Domains (2) summary
      cd01161
      Location:72 → 481
      VLCAD; Very long chain acyl-CoA dehydrogenase
      COG1960
      Location:97 → 473
      CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      26934843..26940041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48818.3 GenPept UniProtKB/Swiss-Prot:P48818

    Gene LinkOut

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