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    MED21 mediator complex subunit 21 [ Bos taurus (domestic cattle) ]

    Gene ID: 539496, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MED21provided by VGNC
    Official Full Name
    mediator complex subunit 21provided by VGNC
    Primary source
    VGNC:VGNC:31358
    See related
    BGD:BT22339; Ensembl:ENSBTAG00000005082
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MED21 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (82772589..82782365, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene aryl hydrocarbon receptor nuclear translocator like 2 Neighboring gene serine/threonine kinase 38 like Neighboring gene transmembrane 7 superfamily member 3 Neighboring gene FGFR1 oncogene partner 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC133576

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mediator of RNA polymerase II transcription subunit 21
    Names
    RNA polymerase II holoenzyme component SRB7
    RNAPII complex component SRB7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038566.1 → NP_001033655.1  mediator of RNA polymerase II transcription subunit 21

      Status: PROVISIONAL

      Source sequence(s)
      BC109636
      UniProtKB/Swiss-Prot
      Q2TBU8
      UniProtKB/TrEMBL
      A0AAF6YND6
      Related
      ENSBTAP00000006696.5, ENSBTAT00000006696.6
      Conserved Domains (1) summary
      pfam11221
      Location:1 → 127
      Med21; Subunit 21 of Mediator complex

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      82772589..82782365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886613.1 → XP_059742596.1  mediator of RNA polymerase II transcription subunit 21 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TBU8.1 GenPept UniProtKB/Swiss-Prot:Q2TBU8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials