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    PROCR protein C receptor [ Bos taurus (domestic cattle) ]

    Gene ID: 282005, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PROCRprovided by VGNC
    Official Full Name
    protein C receptorprovided by VGNC
    Primary source
    VGNC:VGNC:33359
    See related
    BGD:BT13648; Ensembl:ENSBTAG00000008291
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    EPCR
    Orthologs
    human mouse all
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    Genomic context

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    See PROCR in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (64441610..64449124)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel subfamily C member 4 associated protein Neighboring gene ER degradation enhancing alpha-mannosidase like protein 2 Neighboring gene matrix metallopeptidase 24 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene MMP24 opposite strand

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR. Fukudome K, et al. J Biol Chem, 1995 Mar 10. PMID 7890676
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endothelial protein C receptor
    Names
    APC receptor
    activated protein C receptor
    endothelial cell protein C receptor
    endothelial cell protein C/activated protein C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174437.1 → NP_776862.1  endothelial protein C receptor precursor

      See identical proteins and their annotated locations for NP_776862.1

      Status: PROVISIONAL

      Source sequence(s)
      L39065
      UniProtKB/Swiss-Prot
      Q1LZD2, Q28105
      UniProtKB/TrEMBL
      A0AAF6YSI3
      Related
      ENSBTAP00000010911.4, ENSBTAT00000010911.5
      Conserved Domains (1) summary
      cl08246
      Location:22 → 192
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      64441610..64449124
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059892393.1 → XP_059748376.1  endothelial protein C receptor isoform X1

      UniProtKB/TrEMBL
      A0AAA9RUZ5, A0AAF6YSI3

    2. XM_059892394.1 → XP_059748377.1  endothelial protein C receptor isoform X1

      UniProtKB/TrEMBL
      A0AAA9RUZ5, A0AAF6YSI3
      Related
      ENSBTAP00000074792.1, ENSBTAT00000124883.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28105.1 GenPept UniProtKB/Swiss-Prot:Q28105

    Gene LinkOut

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