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    CYB5R3 cytochrome b5 reductase 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 515773, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CYB5R3provided by VGNC
    Official Full Name
    cytochrome b5 reductase 3provided by VGNC
    Primary source
    VGNC:VGNC:49054
    See related
    Ensembl:ENSBTAG00000016516
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CYB5R3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (113474020..113498717, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase delta interacting protein 3 Neighboring gene U12 minor spliceosomal RNA Neighboring gene uncharacterized LOC104972597 Neighboring gene alpha 1,4-galactosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Isolation and partial characterization of the NH2-terminal membrane-binding domain of NADH-cytochrome b5 reductase. Kensil CR, et al. J Biol Chem, 1983 Dec 10. PMID 6643503
    2. Identification of the NH2-terminal blocking group of NADH-cytochrome b5 reductase as myristic acid and the complete amino acid sequence of the membrane-binding domain. Ozols J, et al. J Biol Chem, 1984 Nov 10. PMID 6436247
    3. Complete amino acid sequence of steer liver microsomal NADH-cytochrome b5 reductase. Ozols J, et al. J Biol Chem, 1985 Oct 5. PMID 3900065
    4. Structural comparison of bovine erythrocyte, brain, and liver NADH-cytochrome b5 reductase by HPLC mapping. Tamura M, et al. J Biochem, 1987 May. PMID 3654589
    5. Characterization of lysyl residues of NADH-cytochrome b5 reductase implicated in charge-pairing with active-site carboxyl residues of cytochrome b5 by site-directed mutagenesis of an expression vector for the flavoprotein. Strittmatter P, et al. J Biol Chem, 1992 Feb 5. PMID 1370824

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC166196

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADH-cytochrome b5 reductase 3
    Names
    B5R
    diaphorase-1
    NP_001096720.1
    XP_024847495.1
    XP_059742381.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103250.1 → NP_001096720.1  NADH-cytochrome b5 reductase 3

      See identical proteins and their annotated locations for NP_001096720.1

      Status: PROVISIONAL

      Source sequence(s)
      BC146232
      UniProtKB/Swiss-Prot
      A6H7G0, P07514
      UniProtKB/TrEMBL
      A0AAF7AKY8
      Related
      ENSBTAP00000061269.2, ENSBTAT00000086699.2
      Conserved Domains (1) summary
      PLN02252
      Location:38 → 301
      PLN02252; nitrate reductase [NADPH]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      113474020..113498717 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991727.2 → XP_024847495.1  NADH-cytochrome b5 reductase 3 isoform X2

      UniProtKB/TrEMBL
      A0AAF7AKY8
      Conserved Domains (1) summary
      PLN02252
      Location:15 → 278
      PLN02252; nitrate reductase [NADPH]

    2. XM_059886398.1 → XP_059742381.1  NADH-cytochrome b5 reductase 3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9T925, F1N7T1
      Related
      ENSBTAP00000095199.1, ENSBTAT00000132096.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P07514.3 GenPept UniProtKB/Swiss-Prot:P07514

    Gene LinkOut

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