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    SLC6A9 solute carrier family 6 member 9 [ Bos taurus (domestic cattle) ]

    Gene ID: 282368, updated on 1-Jan-2025

    Summary

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    Gene symbol
    SLC6A9
    Gene description
    solute carrier family 6 member 9
    See related
    BGD:BT11696; Ensembl:ENSBTAG00000008690
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    glyT1; glyT-1
    Orthologs
    human mouse all
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    Genomic context

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    See SLC6A9 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (102033426..102065123)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene KLF transcription factor 17 Neighboring gene dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial-like Neighboring gene uncharacterized LOC112446027 Neighboring gene coiled-coil domain containing 24 Neighboring gene beta-1,4-galactosyltransferase 2 Neighboring gene ATPase H+ transporting V0 subunit b

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A second generation radiation hybrid map to aid the assembly of the bovine genome sequence. Jann OC, et al. BMC Genomics, 2006 Nov 6. PMID 17087818, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glycine:sodium symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycine import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glycinergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium- and chloride-dependent glycine transporter 1
    Names
    solute carrier family 6 (neurotransmitter transporter, glycine), member 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242342.1 → NP_001229271.1  sodium- and chloride-dependent glycine transporter 1 isoform 2

      See identical proteins and their annotated locations for NP_001229271.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      BC134579, EH146991, U52688
      UniProtKB/TrEMBL
      A4IFH2, F1N097, F6Q5E2
      Related
      ENSBTAP00000011454.5, ENSBTAT00000011454.5
      Conserved Domains (1) summary
      cd11498
      Location:11 → 594
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    2. NM_001242343.1 → NP_001229272.1  sodium- and chloride-dependent glycine transporter 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).
      Source sequence(s)
      CO877095, DV831128, DV869417, EV618720, U52687, U52688
      UniProtKB/Swiss-Prot
      Q28039, Q28040, Q29420
      UniProtKB/TrEMBL
      A0A3Q1M4J5
      Related
      ENSBTAP00000064736.1, ENSBTAT00000079705.1
      Conserved Domains (1) summary
      cd11498
      Location:16 → 599
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      102033426..102065123
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005204642.5 → XP_005204699.2  sodium- and chloride-dependent glycine transporter 1 isoform X3

      UniProtKB/TrEMBL
      A0AAA9S6D7
      Conserved Domains (1) summary
      cl00456
      Location:26 → 556
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_005204640.5 → XP_005204697.2  sodium- and chloride-dependent glycine transporter 1 isoform X1

      UniProtKB/TrEMBL
      A4IFH2, F1N097, F6Q5E2
      Conserved Domains (1) summary
      cd11498
      Location:11 → 594
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    3. XM_005204641.5 → XP_005204698.2  sodium- and chloride-dependent glycine transporter 1 isoform X2

      UniProtKB/TrEMBL
      A0AAA9S6D7
      Conserved Domains (1) summary
      cl00456
      Location:57 → 587
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_174612.2: Suppressed sequence

      Description
      NM_174612.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28039.1 GenPept UniProtKB/Swiss-Prot:Q28039

    Gene LinkOut

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