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    HM13 histocompatibility minor 13 [ Bos taurus (domestic cattle) ]

    Gene ID: 512534, updated on 28-Dec-2024

    Summary

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    Official Symbol
    HM13provided by VGNC
    Official Full Name
    histocompatibility minor 13provided by VGNC
    Primary source
    VGNC:VGNC:29868
    See related
    Ensembl:ENSBTAG00000008840
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See HM13 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (61107904..61146837)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene defensin beta 124 Neighboring gene RRAD and GEM like GTPase 1 Neighboring gene microRNA mir-12010 Neighboring gene uncharacterized LOC101906008 Neighboring gene inhibitor of DNA binding 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC134054

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane protein proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal peptide processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic side of endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lumenal side of endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    minor histocompatibility antigen H13
    Names
    minor histocompatibility antigen 13
    NP_001039589.2
    XP_005214721.1
    XP_005214722.1
    XP_024856287.1
    XP_024856289.1
    XP_024856290.1
    XP_024856291.1
    XP_024856292.1
    XP_024856293.1
    XP_059748525.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046124.2 → NP_001039589.2  minor histocompatibility antigen H13

      See identical proteins and their annotated locations for NP_001039589.2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000013
      UniProtKB/TrEMBL
      A0AAA9TM95
      Related
      ENSBTAP00000011640.6, ENSBTAT00000011640.6
      Conserved Domains (1) summary
      pfam04258
      Location:63 → 350
      Peptidase_A22B; Signal peptide peptidase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      61107904..61146837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025000522.2 → XP_024856290.1  minor histocompatibility antigen H13 isoform X5

      UniProtKB/TrEMBL
      A0AAA9TM95
      Conserved Domains (1) summary
      pfam04258
      Location:63 → 368
      Peptidase_A22B; Signal peptide peptidase

    2. XM_005214664.5 → XP_005214721.1  minor histocompatibility antigen H13 isoform X9

      See identical proteins and their annotated locations for XP_005214721.1

      UniProtKB/TrEMBL
      A0A3Q1M7Q7, A0AAA9TM95
      Related
      ENSBTAP00000069886.2, ENSBTAT00000066988.2
      Conserved Domains (1) summary
      pfam04258
      Location:63 → 350
      Peptidase_A22B; Signal peptide peptidase

    3. XM_025000525.2 → XP_024856293.1  minor histocompatibility antigen H13 isoform X7

      UniProtKB/TrEMBL
      A0AAA9TM95
      Conserved Domains (1) summary
      pfam04258
      Location:68 → 317
      Peptidase_A22B; Signal peptide peptidase

    4. XM_025000521.2 → XP_024856289.1  minor histocompatibility antigen H13 isoform X3

      Conserved Domains (1) summary
      pfam04258
      Location:68 → 335
      Peptidase_A22B; Signal peptide peptidase

    5. XM_025000519.2 → XP_024856287.1  minor histocompatibility antigen H13 isoform X1

      UniProtKB/TrEMBL
      A0AAA9RYE6
      Conserved Domains (1) summary
      pfam04258
      Location:63 → 368
      Peptidase_A22B; Signal peptide peptidase

    6. XM_005214665.5 → XP_005214722.1  minor histocompatibility antigen H13 isoform X4

      Conserved Domains (1) summary
      pfam04258
      Location:68 → 317
      Peptidase_A22B; Signal peptide peptidase

    7. XM_059892542.1 → XP_059748525.1  minor histocompatibility antigen H13 isoform X2

      UniProtKB/TrEMBL
      A0AAA9RYE6

    8. XM_025000524.2 → XP_024856292.1  minor histocompatibility antigen H13 isoform X6

      Conserved Domains (1) summary
      cl01342
      Location:63 → 301
      Peptidase_A22B; Signal peptide peptidase

    9. XM_025000523.2 → XP_024856291.1  minor histocompatibility antigen H13 isoform X8

      Conserved Domains (1) summary
      pfam04258
      Location:1 → 303
      Peptidase_A22B; Signal peptide peptidase

    RNA

    1. XR_003037679.2 RNA Sequence

      Related
      ENSBTAT00000132305.1
    Nucleotide Protein Strain
    Heading Accession and Version

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