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    BLVRB biliverdin reductase B [ Bos taurus (domestic cattle) ]

    Gene ID: 281650, updated on 30-Jan-2025

    Summary

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    Official Symbol
    BLVRBprovided by VGNC
    Official Full Name
    biliverdin reductase Bprovided by VGNC
    Primary source
    VGNC:VGNC:26511
    See related
    BGD:BT10362; EnsemblRapid:ENSBTAG00070016558
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See BLVRB in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (49781061..49798076, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene SERTA domain containing 1 Neighboring gene uncharacterized LOC132342850 Neighboring gene SERTA domain containing 3 Neighboring gene spectrin beta, non-erythrocytic 4 Neighboring gene SH3KBP1 binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Flavin reductase: sequence of cDNA from bovine liver and tissue distribution. Quandt KS, et al. Proc Natl Acad Sci U S A, 1994 Sep 27. PMID 7937764, Free PMC Article
    2. Evidence that the protein components of bovine erythrocyte green heme binding protein and flavin reductase are identical. Quandt KS, et al. Biochem Biophys Res Commun, 1991 Jul 15. PMID 2069570
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables biliverdin reductase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables riboflavin reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    flavin reductase (NADPH)
    Names
    BVR-B
    FLR
    FR
    GHBP
    NADPH-dependent diaphorase
    NADPH-flavin reductase
    S-nitroso-CoA-assisted nitrosyltransferase
    SNO-CoA-assisted nitrosyltransferase
    biliverdin-IX beta-reductase
    green heme-binding protein
    NP_776676.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174251.1 → NP_776676.1  flavin reductase (NADPH)

      See identical proteins and their annotated locations for NP_776676.1

      Status: PROVISIONAL

      Source sequence(s)
      L35045
      UniProtKB/Swiss-Prot
      P52556, Q3T0T4
      UniProtKB/TrEMBL
      A0AAA9T7T1
      Related
      ENSBTAP00070021860.1, ENSBTAT00070037168.1
      Conserved Domains (2) summary
      cd05244
      Location:5 → 200
      BVR-B_like_SDR_a; biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs
      COG0451
      Location:4 → 158
      WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49781061..49798076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P52556.2 GenPept UniProtKB/Swiss-Prot:P52556

    Gene LinkOut

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