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    NRBP2 nuclear receptor binding protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 504664, updated on 1-Jan-2025

    Summary

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    Official Symbol
    NRBP2provided by VGNC
    Official Full Name
    nuclear receptor binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:32256
    See related
    BGD:BT14344; Ensembl:ENSBTAG00000008079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NRBP2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (961133..968468)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene plectin Neighboring gene microRNA mir-2309 Neighboring gene epiplakin 1 Neighboring gene poly(U) binding splicing factor 60 Neighboring gene scribble planar cell polarity protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear receptor-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077848.2 → NP_001071316.2  nuclear receptor-binding protein 2

      Status: VALIDATED

      Source sequence(s)
      BC123443, BM435648, DV885547, EE344817, EE364937, NKLS02000014
      UniProtKB/TrEMBL
      F1MGJ6
      Related
      ENSBTAP00000010627.5, ENSBTAT00000010627.7
      Conserved Domains (1) summary
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      961133..968468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215143.5 → XP_005215200.1  nuclear receptor-binding protein 2 isoform X1

      Conserved Domains (2) summary
      smart00220
      Location:54 → 301
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like

    2. XM_005215145.5 → XP_005215202.1  nuclear receptor-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like

    3. XM_005215148.5 → XP_005215205.1  nuclear receptor-binding protein 2 isoform X6

      Conserved Domains (1) summary
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like

    4. XM_005215147.5 → XP_005215204.1  nuclear receptor-binding protein 2 isoform X5

      Conserved Domains (2) summary
      smart00220
      Location:54 → 301
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like

    5. XM_005215144.5 → XP_005215201.1  nuclear receptor-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1N4M9
      Related
      ENSBTAP00000064804.2, ENSBTAT00000086809.2
      Conserved Domains (2) summary
      smart00220
      Location:54 → 301
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like

    6. XM_005215146.5 → XP_005215203.1  nuclear receptor-binding protein 2 isoform X4

      Conserved Domains (1) summary
      cd14035
      Location:44 → 305
      PK_MADML; Pseudokinase domain of MLF1-ADaptor Molecule-Like
    Nucleotide Protein Strain
    Heading Accession and Version

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