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    LRSAM1 leucine rich repeat and sterile alpha motif containing 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 507008, updated on 27-Dec-2024

    Summary

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    Official Symbol
    LRSAM1provided by VGNC
    Official Full Name
    leucine rich repeat and sterile alpha motif containing 1provided by VGNC
    Primary source
    VGNC:VGNC:31045
    See related
    BGD:BT26683; Ensembl:ENSBTAG00000012844
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LRSAM1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (98183914..98217754)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA65 Neighboring gene zinc finger protein 79 Neighboring gene ribosomal protein L12 Neighboring gene niban apoptosis regulator 2 Neighboring gene cytochrome c Neighboring gene syntaxin binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC139439

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase LRSAM1
    NP_001068764.1
    XP_005213269.1
    XP_059747083.1
    XP_059747084.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075296.1 → NP_001068764.1  E3 ubiquitin-protein ligase LRSAM1

      See identical proteins and their annotated locations for NP_001068764.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123396
      UniProtKB/TrEMBL
      A0AAA9S079, Q08E63
      Related
      ENSBTAP00000017067.4, ENSBTAT00000017067.5
      Conserved Domains (6) summary
      sd00033
      Location:33 → 54
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10267
      Location:317 → 416
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
      pfam12799
      Location:128 → 166
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:84 → 139
      LRR_8; Leucine rich repeat
      pfam13920
      Location:675 → 717
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
      cl15755
      Location:567 → 631
      SAM_superfamily; SAM (Sterile alpha motif )

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      98183914..98217754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005213212.5 → XP_005213269.1  E3 ubiquitin-protein ligase LRSAM1 isoform X1

      See identical proteins and their annotated locations for XP_005213269.1

      UniProtKB/TrEMBL
      A0AAA9S079, Q08E63
      Conserved Domains (6) summary
      sd00033
      Location:33 → 54
      LRR_RI; leucine-rich repeat [structural motif]
      pfam10267
      Location:317 → 416
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
      pfam12799
      Location:128 → 166
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:84 → 139
      LRR_8; Leucine rich repeat
      pfam13920
      Location:675 → 717
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
      cl15755
      Location:567 → 631
      SAM_superfamily; SAM (Sterile alpha motif )

    2. XM_059891100.1 → XP_059747083.1  E3 ubiquitin-protein ligase LRSAM1 isoform X2

      UniProtKB/TrEMBL
      A0AAA9S079, A0AAA9THH4
      Related
      ENSBTAP00000096532.1, ENSBTAT00000101368.1

    3. XM_059891101.1 → XP_059747084.1  E3 ubiquitin-protein ligase LRSAM1 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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