U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CLDN18 claudin 18 [ Bos taurus (domestic cattle) ]

    Gene ID: 511460, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CLDN18provided by VGNC
    Official Full Name
    claudin 18provided by VGNC
    Primary source
    VGNC:VGNC:27408
    See related
    BGD:BT17486; Ensembl:ENSBTAG00000014589
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CLDN18 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (131114598..131142080, complement)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene alpha-1,4-N-acetylglucosaminyltransferase Neighboring gene DAZ interacting zinc finger protein 1 like Neighboring gene uncharacterized LOC107132214 Neighboring gene SRY-box transcription factor 14 Neighboring gene transfer RNA glycine (anticodon CCC)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC140810

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    claudin-18

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075516.1 → NP_001068984.1  claudin-18

      See identical proteins and their annotated locations for NP_001068984.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120090
      UniProtKB/Swiss-Prot
      Q0VCN0
      Related
      ENSBTAP00000019421.2, ENSBTAT00000019421.3
      Conserved Domains (1) summary
      cl21598
      Location:7 → 191
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      131114598..131142080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005201865.5 → XP_005201922.1  claudin-18 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SDS4
      Related
      ENSBTAP00000080521.1, ENSBTAT00000097089.1
      Conserved Domains (1) summary
      cl21598
      Location:9 → 191
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VCN0.1 GenPept UniProtKB/Swiss-Prot:Q0VCN0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials