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    MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 532952, updated on 30-Jan-2025

    Summary

    Official Symbol
    MAGI3provided by VGNC
    Official Full Name
    membrane associated guanylate kinase, WW and PDZ domain containing 3provided by VGNC
    Primary source
    VGNC:VGNC:31148
    See related
    EnsemblRapid:ENSBTAG00070036064
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See MAGI3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (29703286..29962560, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene pleckstrin-2-like Neighboring gene uncharacterized LOC132344857 Neighboring gene putative homeodomain transcription factor 1 Neighboring gene uncharacterized LOC101908104 Neighboring gene 60S ribosomal protein L12 pseudogene

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192746.1NP_001179675.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000003
      Conserved Domains (6) summary
      smart00456
      Location:294326
      WW; Domain with 2 conserved Trp (W) residues
      smart00228
      Location:413493
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00201
      Location:342372
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:10221100
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam10500
      Location:12511373
      SR-25; Nuclear RNA-splicing-associated protein
      cl17190
      Location:123197
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29703286..29962560 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005204131.5XP_005204188.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      E1BM96
      Related
      ENSBTAP00070048997.1, ENSBTAT00070080844.1
      Conserved Domains (6) summary
      smart00456
      Location:295327
      WW; Domain with 2 conserved Trp (W) residues
      smart00228
      Location:414494
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00201
      Location:343373
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:10231101
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam10500
      Location:12521374
      SR-25; Nuclear RNA-splicing-associated protein
      cl17190
      Location:123197
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    2. XM_024989434.2XP_024845202.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X2

      Conserved Domains (6) summary
      smart00456
      Location:6799
      WW; Domain with 2 conserved Trp (W) residues
      smart00228
      Location:186266
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00201
      Location:115145
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:795873
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam10500
      Location:10241136
      SR-25; Nuclear RNA-splicing-associated protein
      cl28033
      Location:8901167
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    3. XM_059884664.1XP_059740647.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X4

    4. XM_015463779.3XP_015319265.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MC73
      Conserved Domains (5) summary
      smart00456
      Location:5082
      WW; Domain with 2 conserved Trp (W) residues
      smart00228
      Location:169249
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00201
      Location:98128
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:778856
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam10500
      Location:10071129
      SR-25; Nuclear RNA-splicing-associated protein
    5. XM_010803185.4XP_010801487.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X6

      Conserved Domains (4) summary
      smart00456
      Location:294326
      WW; Domain with 2 conserved Trp (W) residues
      smart00228
      Location:413493
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:10221100
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl17190
      Location:123197
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    6. XM_059884665.1XP_059740648.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X5