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    G2E3 G2/M-phase specific E3 ubiquitin protein ligase [ Bos taurus (domestic cattle) ]

    Gene ID: 508575, updated on 27-Dec-2024

    Summary

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    Official Symbol
    G2E3provided by VGNC
    Official Full Name
    G2/M-phase specific E3 ubiquitin protein ligaseprovided by VGNC
    Primary source
    VGNC:VGNC:29175
    See related
    BGD:BT22925; Ensembl:ENSBTAG00000001617
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See G2E3 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (41190591..41267485)

    Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene uncharacterized LOC112443227 Neighboring gene sec1 family domain containing 1 Neighboring gene oxysterol-binding protein-related protein 9-like Neighboring gene small ribosomal subunit protein eS25-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC133923

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G2/M phase-specific E3 ubiquitin-protein ligase
    Names
    G2/M-phase specific E3 ubiquitin ligase
    NP_001033760.2
    XP_005222097.1
    XP_059734970.1
    XP_059734971.1
    XP_059734972.1
    XP_059734973.1
    XP_059734974.1
    XP_059734975.1
    XP_059734976.1
    XP_059734977.1
    XP_059734978.1
    XP_059734979.1
    XP_059734980.1
    XP_059734981.1
    XP_059734982.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038671.2 → NP_001033760.2  G2/M phase-specific E3 ubiquitin-protein ligase

      See identical proteins and their annotated locations for NP_001033760.2

      Status: INFERRED

      Source sequence(s)
      NKLS02000021
      UniProtKB/TrEMBL
      A0AAA9TEU4, F1N5U1
      Related
      ENSBTAP00000002121.5, ENSBTAT00000002121.6
      Conserved Domains (3) summary
      cd15496
      Location:232 → 285
      PHD_PHF7_G2E3_like; PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
      cd15669
      Location:14 → 127
      ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
      cl27008
      Location:413 → 691
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      41190591..41267485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059878991.1 → XP_059734974.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X3

      UniProtKB/TrEMBL
      A0AAA9TEU4

    2. XM_059878997.1 → XP_059734980.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X6

      UniProtKB/TrEMBL
      A0AAA9TEU4

    3. XM_059878987.1 → XP_059734970.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MD32, A0AAA9TEU4
      Related
      ENSBTAP00000068812.2, ENSBTAT00000081132.2

    4. XM_059878988.1 → XP_059734971.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X2

      UniProtKB/TrEMBL
      A0AAA9TEU4

    5. XM_005222040.5 → XP_005222097.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X5

      See identical proteins and their annotated locations for XP_005222097.1

      UniProtKB/TrEMBL
      A0AAA9SMJ7, A0AAA9TEU4
      Related
      ENSBTAP00000087581.1, ENSBTAT00000098074.1
      Conserved Domains (4) summary
      smart00119
      Location:414 → 716
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      cd15496
      Location:257 → 310
      PHD_PHF7_G2E3_like; PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
      cd15669
      Location:39 → 152
      ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
      cl00077
      Location:438 → 716
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    6. XM_059878994.1 → XP_059734977.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X4

      UniProtKB/TrEMBL
      A0AAA9TEU4

    7. XM_059878995.1 → XP_059734978.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X6

      UniProtKB/TrEMBL
      A0AAA9TEU4

    8. XM_059878999.1 → XP_059734982.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X7

    9. XM_059878993.1 → XP_059734976.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X3

      UniProtKB/TrEMBL
      A0AAA9TEU4

    10. XM_059878992.1 → XP_059734975.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X3

      UniProtKB/TrEMBL
      A0AAA9TEU4

    11. XM_059878996.1 → XP_059734979.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X6

      UniProtKB/TrEMBL
      A0AAA9TEU4

    12. XM_059878990.1 → XP_059734973.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X3

      UniProtKB/TrEMBL
      A0AAA9TEU4

    13. XM_059878998.1 → XP_059734981.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X6

      UniProtKB/TrEMBL
      A0AAA9TEU4

    14. XM_059878989.1 → XP_059734972.1  G2/M phase-specific E3 ubiquitin-protein ligase isoform X3

      UniProtKB/TrEMBL
      A0AAA9TEU4
    Nucleotide Protein Strain
    Heading Accession and Version

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