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    TOR2A torsin family 2 member A [ Bos taurus (domestic cattle) ]

    Gene ID: 534311, updated on 27-Dec-2024

    Summary

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    Official Symbol
    TOR2Aprovided by VGNC
    Official Full Name
    torsin family 2 member Aprovided by VGNC
    Primary source
    VGNC:VGNC:49983
    See related
    BGD:BT12068; Ensembl:ENSBTAG00000013510
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    Torsin-2A; Prosalusin
    Orthologs
    human mouse all
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    Genomic context

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    See TOR2A in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (98411725..98415754, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 1 Neighboring gene cytochrome c Neighboring gene cilia and flagella associated protein 157 Neighboring gene peptidyl-tRNA hydrolase 1 homolog Neighboring gene tetratricopeptide repeat domain 16 Neighboring gene SH2 domain containing 3C Neighboring gene cyclin dependent kinase 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC140387

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chaperone cofactor-dependent protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    torsin-2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083476.2 → NP_001076945.1  torsin-2A precursor

      See identical proteins and their annotated locations for NP_001076945.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114885
      UniProtKB/Swiss-Prot
      A4FUH1
      Related
      ENSBTAP00000017963.4, ENSBTAT00000017963.6
      Conserved Domains (2) summary
      smart00382
      Location:85 → 217
      AAA; ATPases associated with a variety of cellular activities
      cl21455
      Location:35 → 160
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      98411725..98415754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005213302.5 → XP_005213359.1  torsin-2A isoform X1

      See identical proteins and their annotated locations for XP_005213359.1

      UniProtKB/Swiss-Prot
      P0C7W1
      Related
      ENSBTAP00000080721.1, ENSBTAT00000110988.1
      Conserved Domains (2) summary
      smart00382
      Location:85 → 197
      AAA; ATPases associated with a variety of cellular activities
      cl21455
      Location:35 → 160
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4FUH1.1 GenPept UniProtKB/Swiss-Prot:A4FUH1
    P0C7W1.1 GenPept UniProtKB/Swiss-Prot:P0C7W1

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