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    APC APC regulator of WNT signaling pathway [ Bos taurus (domestic cattle) ]

    Gene ID: 533233, updated on 27-Dec-2024

    Summary

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    Official Symbol
    APCprovided by VGNC
    Official Full Name
    APC regulator of WNT signaling pathwayprovided by VGNC
    Primary source
    VGNC:VGNC:55103
    See related
    BGD:BT18786; Ensembl:ENSBTAG00000018852
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See APC in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (1167671..1299376, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346321 Neighboring gene signal recognition particle 19 Neighboring gene erythrocyte membrane protein band 4.1 like 4A Neighboring gene small nucleolar RNA SNORA13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Establishment of a high throughput EST sequencing system using poly(A) tail-removed cDNA libraries and determination of 36,000 bovine ESTs. Takasuga A, et al. Nucleic Acids Res, 2001 Nov 15. PMID 11713328, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC140121

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables gamma-catenin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell fate specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of microtubule depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pattern specification process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of beta-catenin destruction complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of catenin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenomatous polyposis coli protein
    Names
    APC, WNT signaling pathway regulator
    adenomatosis polyposis coli

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075986.2 → NP_001069454.2  adenomatous polyposis coli protein

      See identical proteins and their annotated locations for NP_001069454.2

      Status: VALIDATED

      Source sequence(s)
      AAFC03000697, AAFC03020263
      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Related
      ENSBTAP00000057792.2, ENSBTAT00000086393.2
      Conserved Domains (17) summary
      smart00185
      Location:649 → 689
      ARM; Armadillo/beta-catenin-like repeats
      pfam00514
      Location:691 → 731
      Arm; Armadillo/beta-catenin-like repeat
      pfam16689
      Location:4 → 55
      APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
      sd00043
      Location:465 → 508
      ARM; armadillo repeat [structural motif]
      pfam05923
      Location:1643 → 1666
      APC_r; APC repeat
      pfam05924
      Location:2040 → 2059
      SAMP; SAMP Motif
      pfam05937
      Location:2677 → 2851
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2230 → 2575
      APC_basic; APC basic domain
      pfam11414
      Location:127 → 207
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:732 → 1018
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1036 → 1135
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1285 → 1370
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1668 → 1721
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1752 → 1845
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1879 → 1953
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      cl21727
      Location:563 → 734
      VATPase_H; VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The ...
      cl25732
      Location:14 → 262
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      1167671..1299376 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005211202.5 → XP_005211259.1  adenomatous polyposis coli protein isoform X12

      UniProtKB/TrEMBL
      A0A3Q1LPA1
      Conserved Domains (13) summary
      cd00020
      Location:520 → 640
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1552 → 1576
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:1950 → 1969
      SAMP; SAMP Motif
      pfam05937
      Location:2586 → 2760
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2139 → 2484
      APC_basic; APC basic domain
      pfam11414
      Location:137 → 217
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:641 → 928
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:945 → 1044
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1194 → 1279
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1577 → 1633
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1654 → 1754
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1791 → 1862
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:374 → 417
      ARM; armadillo repeat [structural motif]

    2. XM_005211196.5 → XP_005211253.1  adenomatous polyposis coli protein isoform X7

      UniProtKB/TrEMBL
      A0A3Q1LPA1, A0A3Q1MUQ9
      Related
      ENSBTAP00000074371.1, ENSBTAT00000072901.2
      Conserved Domains (13) summary
      cd00020
      Location:621 → 741
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1653 → 1677
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:2051 → 2070
      SAMP; SAMP Motif
      pfam05937
      Location:2687 → 2861
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2240 → 2585
      APC_basic; APC basic domain
      pfam11414
      Location:137 → 217
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:742 → 1029
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1046 → 1145
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1295 → 1380
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1678 → 1734
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1755 → 1855
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1892 → 1963
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:475 → 518
      ARM; armadillo repeat [structural motif]

    3. XM_010808816.4 → XP_010807118.1  adenomatous polyposis coli protein isoform X5

      UniProtKB/TrEMBL
      A0A3Q1LPA1
      Conserved Domains (13) summary
      cd00020
      Location:639 → 759
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1671 → 1695
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:2069 → 2088
      SAMP; SAMP Motif
      pfam05937
      Location:2705 → 2879
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2258 → 2603
      APC_basic; APC basic domain
      pfam11414
      Location:137 → 217
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:760 → 1047
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1064 → 1163
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1313 → 1398
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1696 → 1752
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1773 → 1873
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1910 → 1981
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:591 → 623
      ARM; armadillo repeat [structural motif]

    4. XM_059890492.1 → XP_059746475.1  adenomatous polyposis coli protein isoform X10

      UniProtKB/TrEMBL
      A0A3Q1LMC7

    5. XM_015472986.3 → XP_015328472.1  adenomatous polyposis coli protein isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Conserved Domains (13) summary
      cd00020
      Location:571 → 691
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1603 → 1627
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:2001 → 2020
      SAMP; SAMP Motif
      pfam05937
      Location:2637 → 2811
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2190 → 2535
      APC_basic; APC basic domain
      pfam11414
      Location:137 → 217
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:692 → 979
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:996 → 1095
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1245 → 1330
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1628 → 1684
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1705 → 1805
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1842 → 1913
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:523 → 555
      ARM; armadillo repeat [structural motif]

    6. XM_015472983.3 → XP_015328469.1  adenomatous polyposis coli protein isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Conserved Domains (13) summary
      cd00020
      Location:654 → 774
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1686 → 1710
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:2084 → 2103
      SAMP; SAMP Motif
      pfam05937
      Location:2720 → 2894
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2273 → 2618
      APC_basic; APC basic domain
      pfam11414
      Location:137 → 217
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:775 → 1062
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1079 → 1178
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1328 → 1413
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1711 → 1767
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1788 → 1888
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1925 → 1996
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:508 → 551
      ARM; armadillo repeat [structural motif]

    7. XM_015472979.3 → XP_015328465.1  adenomatous polyposis coli protein isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Conserved Domains (13) summary
      cd00020
      Location:672 → 792
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1704 → 1728
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:2102 → 2121
      SAMP; SAMP Motif
      pfam05937
      Location:2738 → 2912
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2291 → 2636
      APC_basic; APC basic domain
      pfam11414
      Location:137 → 217
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:793 → 1080
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1097 → 1196
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1346 → 1431
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1729 → 1785
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1806 → 1906
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1943 → 2014
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:624 → 656
      ARM; armadillo repeat [structural motif]

    8. XM_059890489.1 → XP_059746472.1  adenomatous polyposis coli protein isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LMC7

    9. XM_059890494.1 → XP_059746477.1  adenomatous polyposis coli protein isoform X13

      UniProtKB/TrEMBL
      A0A3Q1LMC7

    10. XM_059890493.1 → XP_059746476.1  adenomatous polyposis coli protein isoform X11

      UniProtKB/TrEMBL
      A0A3Q1LMC7

    11. XM_024997641.2 → XP_024853409.1  adenomatous polyposis coli protein isoform X8

      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Related
      ENSBTAP00000061149.2, ENSBTAT00000070251.2
      Conserved Domains (17) summary
      smart00185
      Location:649 → 689
      ARM; Armadillo/beta-catenin-like repeats
      pfam00514
      Location:691 → 731
      Arm; Armadillo/beta-catenin-like repeat
      pfam16689
      Location:4 → 55
      APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
      sd00043
      Location:465 → 508
      ARM; armadillo repeat [structural motif]
      pfam05923
      Location:1643 → 1666
      APC_r; APC repeat
      pfam05924
      Location:2040 → 2059
      SAMP; SAMP Motif
      pfam05937
      Location:2677 → 2851
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2230 → 2575
      APC_basic; APC basic domain
      pfam11414
      Location:127 → 207
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:732 → 1018
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1036 → 1135
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1285 → 1370
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1668 → 1721
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1752 → 1845
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1879 → 1953
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      cl21727
      Location:563 → 734
      VATPase_H; VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The ...
      cl25732
      Location:14 → 262
      SMC_N; RecF/RecN/SMC N terminal domain

    12. XM_059890490.1 → XP_059746473.1  adenomatous polyposis coli protein isoform X6

      UniProtKB/TrEMBL
      A0A3Q1LMC7, F1MV51
      Related
      ENSBTAP00000025099.6, ENSBTAT00000025099.7

    13. XM_015472981.3 → XP_015328467.1  adenomatous polyposis coli protein isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Conserved Domains (14) summary
      cd00020
      Location:662 → 782
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1694 → 1718
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:2092 → 2111
      SAMP; SAMP Motif
      pfam05937
      Location:2728 → 2902
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2281 → 2626
      APC_basic; APC basic domain
      pfam11414
      Location:127 → 207
      Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
      pfam16629
      Location:783 → 1070
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:1087 → 1186
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1336 → 1421
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1719 → 1775
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1796 → 1896
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1933 → 2004
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:4 → 55
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      sd00043
      Location:614 → 646
      ARM; armadillo repeat [structural motif]

    14. XM_059890491.1 → XP_059746474.1  adenomatous polyposis coli protein isoform X8

      UniProtKB/TrEMBL
      A0A3Q1LMC7
      Related
      ENSBTAP00000056724.2, ENSBTAT00000075487.2

    15. XM_015472988.3 → XP_015328474.1  adenomatous polyposis coli protein isoform X14

      UniProtKB/TrEMBL
      A0A3Q1N9U7
      Related
      ENSBTAP00000067952.2, ENSBTAT00000067496.2
      Conserved Domains (12) summary
      cd00020
      Location:479 → 599
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam05923
      Location:1511 → 1535
      APC_crr; APC cysteine-rich region
      pfam05924
      Location:1909 → 1928
      SAMP; SAMP Motif
      pfam05937
      Location:2545 → 2719
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:2098 → 2443
      APC_basic; APC basic domain
      pfam16629
      Location:600 → 887
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:904 → 1003
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:1153 → 1238
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:1536 → 1592
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:1613 → 1713
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:1750 → 1821
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      sd00043
      Location:431 → 463
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein Strain
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