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    DBF4 DBF4 zinc finger [ Bos taurus (domestic cattle) ]

    Gene ID: 510916, updated on 1-Jan-2025

    Summary

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    Official Symbol
    DBF4provided by VGNC
    Official Full Name
    DBF4 zinc fingerprovided by VGNC
    Primary source
    VGNC:VGNC:27887
    See related
    Ensembl:ENSBTAG00000014711
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See DBF4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (32287898..32314942, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene transformer 2 alpha homolog Neighboring gene coiled-coil domain containing 126 Neighboring gene solute carrier family 25, member 40 Neighboring gene uncharacterized LOC785370

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC139071

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of nuclear cell cycle DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell cycle phase transition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Dbf4-dependent protein kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein DBF4 homolog A
    Names
    activator of S phase kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      32287898..32314942 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005205256.5 → XP_005205313.1  protein DBF4 homolog A isoform X1

      UniProtKB/TrEMBL
      E1BCW4
      Related
      ENSBTAP00000035016.5, ENSBTAT00000035138.6
      Conserved Domains (2) summary
      pfam00533
      Location:42 → 109
      BRCT; BRCA1 C Terminus (BRCT) domain
      cl02684
      Location:289 → 336
      zf-DBF; DBF zinc finger

    2. XM_059885823.1 → XP_059741806.1  protein DBF4 homolog A isoform X2

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001075476.2: Suppressed sequence

      Description
      NM_001075476.2: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

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