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    ANKIB1 ankyrin repeat and IBR domain containing 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 505204, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ANKIB1provided by VGNC
    Official Full Name
    ankyrin repeat and IBR domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:25902
    See related
    BGD:BT12648; Ensembl:ENSBTAG00000034936
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ANKIB1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (9567912..9725826)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene leucine rich repeats and death domain containing 1 Neighboring gene uncharacterized LOC112446355 Neighboring gene KRIT1 ankyrin repeat containing Neighboring gene small ribosomal subunit protein uS8-like Neighboring gene microRNA mir-584-5 Neighboring gene transmembrane BAX inhibitor motif containing 7 Neighboring gene GATA zinc finger domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and IBR domain-containing protein 1
    NP_001178981.1
    XP_024846297.1
    XP_024846298.1
    XP_024846300.1
    XP_059741423.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192052.2 → NP_001178981.1  ankyrin repeat and IBR domain-containing protein 1

      See identical proteins and their annotated locations for NP_001178981.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000004
      UniProtKB/TrEMBL
      A0AAA9SME8, F1MDC0
      Related
      ENSBTAP00000086500.1, ENSBTAT00000128743.1
      Conserved Domains (4) summary
      cd00204
      Location:47 → 195
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:47 → 77
      ANK; ANK repeat [structural motif]
      pfam01485
      Location:403 → 476
      IBR; IBR domain, a half RING-finger domain
      cd16774
      Location:333 → 389
      RING-HC_RBR_ANKIB1; RING finger, HC subclass, found in ankyrin repeat and IBR domain-containing protein 1 (ANKIB1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      9567912..9725826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990530.2 → XP_024846298.1  ankyrin repeat and IBR domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SME8, F1MDC0
      Related
      ENSBTAP00000083925.1, ENSBTAT00000107522.1
      Conserved Domains (4) summary
      cd00204
      Location:47 → 195
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:47 → 77
      ANK; ANK repeat [structural motif]
      pfam01485
      Location:403 → 476
      IBR; IBR domain, a half RING-finger domain
      cd16774
      Location:333 → 389
      RING-HC_RBR_ANKIB1; RING finger, HC subclass, found in ankyrin repeat and IBR domain-containing protein 1 (ANKIB1) and similar proteins

    2. XM_024990529.2 → XP_024846297.1  ankyrin repeat and IBR domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      F1MDC0
      Conserved Domains (4) summary
      cd00204
      Location:47 → 195
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:47 → 77
      ANK; ANK repeat [structural motif]
      pfam01485
      Location:403 → 476
      IBR; IBR domain, a half RING-finger domain
      cd16774
      Location:333 → 389
      RING-HC_RBR_ANKIB1; RING finger, HC subclass, found in ankyrin repeat and IBR domain-containing protein 1 (ANKIB1) and similar proteins

    3. XM_024990532.2 → XP_024846300.1  ankyrin repeat and IBR domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      F1MDC0
      Conserved Domains (2) summary
      pfam01485
      Location:202 → 275
      IBR; IBR domain, a half RING-finger domain
      cd16774
      Location:132 → 188
      RING-HC_RBR_ANKIB1; RING finger, HC subclass, found in ankyrin repeat and IBR domain-containing protein 1 (ANKIB1) and similar proteins

    4. XM_059885440.1 → XP_059741423.1  ankyrin repeat and IBR domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      F1MDC0
    Nucleotide Protein Strain
    Heading Accession and Version

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