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    APBB3 amyloid beta precursor protein binding family B member 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 525278, updated on 27-Dec-2024

    Summary

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    Official Symbol
    APBB3provided by VGNC
    Official Full Name
    amyloid beta precursor protein binding family B member 3provided by VGNC
    Primary source
    VGNC:VGNC:50070
    See related
    BGD:BT29283; Ensembl:ENSBTAG00000001450
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See APBB3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (51731682..51737933, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and KH domain containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene steroid receptor RNA activator 1 Neighboring gene eukaryotic translation initiation factor 4E binding protein 3 Neighboring gene uncharacterized LOC112447435 Neighboring gene SLC35A4 upstream open reading frame protein Neighboring gene uncharacterized LOC509618 Neighboring gene solute carrier family 35 member A4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC142933

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amyloid-beta binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amyloid-beta A4 precursor protein-binding family B member 3
    Names
    amyloid beta (A4) precursor protein-binding, family B, member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075867.1 → NP_001069335.1  amyloid-beta A4 precursor protein-binding family B member 3

      See identical proteins and their annotated locations for NP_001069335.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120443
      UniProtKB/TrEMBL
      F1N3C4, Q0VBY6
      Conserved Domains (3) summary
      smart00456
      Location:30 → 61
      WW; Domain with 2 conserved Trp (W) residues
      cd01271
      Location:283 → 413
      PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
      cd01272
      Location:116 → 254
      PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      51731682..51737933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059888210.1 → XP_059744193.1  amyloid-beta A4 precursor protein-binding family B member 3 isoform X2

      UniProtKB/TrEMBL
      F1N3C4

    2. XM_005209456.4 → XP_005209513.1  amyloid-beta A4 precursor protein-binding family B member 3 isoform X3

      UniProtKB/TrEMBL
      F1N3C4
      Related
      ENSBTAP00000040787.3, ENSBTAT00000043198.3
      Conserved Domains (3) summary
      smart00456
      Location:30 → 61
      WW; Domain with 2 conserved Trp (W) residues
      cd01271
      Location:281 → 411
      PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
      cd01272
      Location:116 → 252
      PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

    3. XM_024994277.2 → XP_024850045.1  amyloid-beta A4 precursor protein-binding family B member 3 isoform X1

      UniProtKB/TrEMBL
      F1N3C4
      Conserved Domains (3) summary
      smart00456
      Location:30 → 61
      WW; Domain with 2 conserved Trp (W) residues
      cd01271
      Location:281 → 427
      PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
      cd01272
      Location:116 → 252
      PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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