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    MLXIP MLX interacting protein [ Bos taurus (domestic cattle) ]

    Gene ID: 783217, updated on 1-Jan-2025

    Summary

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    Official Symbol
    MLXIPprovided by VGNC
    Official Full Name
    MLX interacting proteinprovided by VGNC
    Primary source
    VGNC:VGNC:31509
    See related
    BGD:BT24148; Ensembl:ENSBTAG00000004189
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See MLXIP in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (53223799..53284518, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 Neighboring gene leucine rich repeat containing 43 Neighboring gene large ribosomal subunit protein uL30-like Neighboring gene uncharacterized LOC112442004 Neighboring gene uncharacterized LOC112442104 Neighboring gene BAF chromatin remodeling complex subunit BCL7A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MLX-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205436.2 → NP_001192365.1  MLX-interacting protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000017
      Conserved Domains (2) summary
      cd00083
      Location:726 → 782
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam06005
      Location:768 → 808
      DUF904; Protein of unknown function (DUF904)

    2. NM_001369916.1 → NP_001356845.1  MLX-interacting protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000017
      Conserved Domains (3) summary
      PHA03247
      Location:348 → 720
      PHA03247; large tegument protein UL36; Provisional
      cd00083
      Location:738 → 794
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cl11531
      Location:780 → 820
      ZapB; Cell division protein ZapB

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53223799..53284518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977495.2 → XP_024833263.1  MLX-interacting protein isoform X2

      Conserved Domains (3) summary
      cd00083
      Location:738 → 795
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam06005
      Location:781 → 821
      ZapB; Cell division protein ZapB
      cl26464
      Location:348 → 720
      Atrophin-1; Atrophin-1 family

    2. XM_024977494.2 → XP_024833262.1  MLX-interacting protein isoform X3

      UniProtKB/TrEMBL
      E1BIZ7
      Related
      ENSBTAP00000005486.6, ENSBTAT00000005486.7
      Conserved Domains (3) summary
      cd00083
      Location:739 → 795
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam06005
      Location:781 → 821
      ZapB; Cell division protein ZapB
      cl26464
      Location:348 → 721
      Atrophin-1; Atrophin-1 family

    3. XM_024977493.2 → XP_024833261.1  MLX-interacting protein isoform X1

      Conserved Domains (3) summary
      cd00083
      Location:739 → 796
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam06005
      Location:782 → 822
      ZapB; Cell division protein ZapB
      cl26464
      Location:348 → 721
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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