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    ZNRF1 zinc and ring finger 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509076, updated on 1-Jan-2025

    Summary

    Official Symbol
    ZNRF1provided by VGNC
    Official Full Name
    zinc and ring finger 1provided by VGNC
    Primary source
    VGNC:VGNC:37363
    See related
    BGD:BT16818; Ensembl:ENSBTAG00000034689
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See ZNRF1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (2362988..2451062)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene fatty acid 2-hydroxylase Neighboring gene uncharacterized LOC132342771 Neighboring gene WD repeat domain 59 Neighboring gene lactate dehydrogenase D Neighboring gene ZFP1 zinc finger protein

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase ZNRF1
    Names
    RING-type E3 ubiquitin transferase ZNRF1
    zinc/RING finger protein 1
    NP_001179139.1
    XP_005218391.1
    XP_005218392.1
    XP_005218393.1
    XP_005218394.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192210.1NP_001179139.1  E3 ubiquitin-protein ligase ZNRF1

      See identical proteins and their annotated locations for NP_001179139.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/Swiss-Prot
      F1MM41
      Related
      ENSBTAP00000046062.5, ENSBTAT00000049126.5
      Conserved Domains (1) summary
      pfam13639
      Location:182222
      zf-RING_2; Ring finger domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2362988..2451062
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005218337.4XP_005218394.1  E3 ubiquitin-protein ligase ZNRF1 isoform X1

      See identical proteins and their annotated locations for XP_005218394.1

      UniProtKB/Swiss-Prot
      F1MM41
      Conserved Domains (1) summary
      pfam13639
      Location:182222
      zf-RING_2; Ring finger domain
    2. XM_005218335.5XP_005218392.1  E3 ubiquitin-protein ligase ZNRF1 isoform X1

      See identical proteins and their annotated locations for XP_005218392.1

      UniProtKB/Swiss-Prot
      F1MM41
      Conserved Domains (1) summary
      pfam13639
      Location:182222
      zf-RING_2; Ring finger domain
    3. XM_005218336.5XP_005218393.1  E3 ubiquitin-protein ligase ZNRF1 isoform X1

      See identical proteins and their annotated locations for XP_005218393.1

      UniProtKB/Swiss-Prot
      F1MM41
      Conserved Domains (1) summary
      pfam13639
      Location:182222
      zf-RING_2; Ring finger domain
    4. XM_005218334.5XP_005218391.1  E3 ubiquitin-protein ligase ZNRF1 isoform X1

      See identical proteins and their annotated locations for XP_005218391.1

      UniProtKB/Swiss-Prot
      F1MM41
      Conserved Domains (1) summary
      pfam13639
      Location:182222
      zf-RING_2; Ring finger domain