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    TTLL1 TTL family tubulin polyglutamylase complex subunit L1 [ Bos taurus (domestic cattle) ]

    Gene ID: 539530, updated on 27-Dec-2024

    Summary

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    Official Symbol
    TTLL1provided by VGNC
    Official Full Name
    TTL family tubulin polyglutamylase complex subunit L1provided by VGNC
    Primary source
    VGNC:VGNC:36489
    See related
    BGD:BT24235; Ensembl:ENSBTAG00000012030
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TTLL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (113827086..113862384, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene uncharacterized LOC101904078 Neighboring gene mitochondrial import inner membrane translocase subunit TIM14-like Neighboring gene BCL2 interacting killer

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC142767

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tubulin-glutamic acid ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyglutamylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    polyglutamylase complex subunit TTLL1
    Names
    PGs3
    probable tubulin polyglutamylase TTLL1
    tubulin polyglutamylase TTLL1
    tubulin polyglutamylase complex subunit 3
    tubulin tyrosine ligase like 1
    tubulin tyrosine ligase-like family, member 1
    tubulin--tyrosine ligase-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076171.1 → NP_001069639.1  polyglutamylase complex subunit TTLL1

      See identical proteins and their annotated locations for NP_001069639.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120322
      UniProtKB/Swiss-Prot
      Q0VC71
      UniProtKB/TrEMBL
      A0AAA9SF75
      Related
      ENSBTAP00000015956.3, ENSBTAT00000015956.5
      Conserved Domains (1) summary
      pfam03133
      Location:59 → 364
      TTL; Tubulin-tyrosine ligase family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      113827086..113862384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024992010.2 → XP_024847778.1  polyglutamylase complex subunit TTLL1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SF75
      Related
      ENSBTAP00000082487.1, ENSBTAT00000114255.1
      Conserved Domains (1) summary
      pfam03133
      Location:59 → 377
      TTL; Tubulin-tyrosine ligase family

    2. XM_005207418.3 → XP_005207475.1  polyglutamylase complex subunit TTLL1 isoform X2

      See identical proteins and their annotated locations for XP_005207475.1

      UniProtKB/Swiss-Prot
      Q0VC71
      UniProtKB/TrEMBL
      A0AAA9SF75
      Conserved Domains (1) summary
      pfam03133
      Location:59 → 364
      TTL; Tubulin-tyrosine ligase family

    3. XM_024992009.2 → XP_024847777.1  polyglutamylase complex subunit TTLL1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SF75
      Conserved Domains (1) summary
      pfam03133
      Location:59 → 377
      TTL; Tubulin-tyrosine ligase family

    4. XM_005207417.5 → XP_005207474.1  polyglutamylase complex subunit TTLL1 isoform X2

      See identical proteins and their annotated locations for XP_005207474.1

      UniProtKB/Swiss-Prot
      Q0VC71
      UniProtKB/TrEMBL
      A0AAA9SF75
      Conserved Domains (1) summary
      pfam03133
      Location:59 → 364
      TTL; Tubulin-tyrosine ligase family

    5. XM_059886615.1 → XP_059742598.1  polyglutamylase complex subunit TTLL1 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SF75

    6. XM_024992008.2 → XP_024847776.1  polyglutamylase complex subunit TTLL1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SF75
      Conserved Domains (1) summary
      pfam03133
      Location:59 → 377
      TTL; Tubulin-tyrosine ligase family

    7. XM_059886614.1 → XP_059742597.1  polyglutamylase complex subunit TTLL1 isoform X3

      UniProtKB/TrEMBL
      A0AAA9SF75

    8. XM_024992012.2 → XP_024847780.1  polyglutamylase complex subunit TTLL1 isoform X6

      Conserved Domains (1) summary
      pfam03133
      Location:59 → 340
      TTL; Tubulin-tyrosine ligase family

    9. XM_024992011.2 → XP_024847779.1  polyglutamylase complex subunit TTLL1 isoform X5

      Conserved Domains (1) summary
      pfam03133
      Location:59 → 339
      TTL; Tubulin-tyrosine ligase family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VC71.1 GenPept UniProtKB/Swiss-Prot:Q0VC71

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