SUCLA2 succinate-CoA ligase ADP-forming subunit beta [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: SUCLA2provided by VGNC
Official Full Name: succinate-CoA ligase ADP-forming subunit betaprovided by VGNC
Primary source: VGNC:VGNC:35455
See related: BGD:BT11481; Ensembl:ENSBTAG00000006759
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: A-SCS
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	12	NC_037339.1 (17809327..17853938, complement)

Chromosome 12 - NC_037339.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables succinate-CoA ligase (ADP-forming) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in succinyl-CoA metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed
part_of succinate-CoA ligase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

Names: ATP-specific succinyl-CoA synthetase subunit beta; SCS-betaA; succinate-CoA ligase ADP-forming beta subunit; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; succinyl-CoA synthetase beta-A chain

NP_001068961.1

EC 6.2.1.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001075493.1 → NP_001068961.1 succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

See identical proteins and their annotated locations for NP_001068961.1

Status: PROVISIONAL

Source sequence(s)

BC118443

UniProtKB/Swiss-Prot

Q148D5

UniProtKB/TrEMBL

A0AAA9S2W7

Related

ENSBTAP00070035825.1, ENSBTAT00070060386.1

Conserved Domains (3) summary

PRK00696
Location:55 → 445

sucC; succinyl-CoA synthetase subunit beta; Provisional

pfam00549
Location:321 → 441

Ligase_CoA; CoA-ligase

pfam08442
Location:55 → 262

ATP-grasp_2; ATP-grasp domain