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    CACNA1H calcium voltage-gated channel subunit alpha1 H [ Bos taurus (domestic cattle) ]

    Gene ID: 282412, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CACNA1Hprovided by VGNC
    Official Full Name
    calcium voltage-gated channel subunit alpha1 Hprovided by VGNC
    Primary source
    VGNC:VGNC:26678
    See related
    BGD:BT16533; Ensembl:ENSBTAG00000026461
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CACNA1H in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (960329..988925)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 8 Neighboring gene tektin 4 Neighboring gene tryptase-2-like Neighboring gene tryptase beta 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion. Enyeart JJ, et al. Am J Physiol Cell Physiol, 2015 Jun 1. PMID 25788571, Free PMC Article
    2. alpha1H T-type Ca2+ channel is the predominant subtype expressed in bovine and rat zona glomerulosa. Schrier AD, et al. Am J Physiol Cell Physiol, 2001 Feb. PMID 11208520
    3. Greater diversity than previously thought of chromaffin cell Ca2+ channels, derived from mRNA identification studies. García-Palomero E, et al. FEBS Lett, 2000 Sep 22. PMID 11007970
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Adrenal fasciculata cells express Cav1.3 and Cav3.2 calcium channels that regulate cortisol secretion.
      Title: Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables low voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion import IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of calcium ion-dependent exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    voltage-dependent T-type calcium channel subunit alpha-1H
    Names
    calcium channel, voltage-dependent, alpha 1H subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      960329..988925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985430.2 → XP_024841198.2  voltage-dependent T-type calcium channel subunit alpha-1H isoform X3

      UniProtKB/TrEMBL
      F1MQV2

    2. XM_024985428.2 → XP_024841196.2  voltage-dependent T-type calcium channel subunit alpha-1H isoform X1

      UniProtKB/TrEMBL
      F1MQV2
      Related
      ENSBTAP00000012991.7, ENSBTAT00000012991.7

    3. XM_024985429.2 → XP_024841197.2  voltage-dependent T-type calcium channel subunit alpha-1H isoform X2

      UniProtKB/TrEMBL
      A0A3Q1NAD2, F1MQV2
      Related
      ENSBTAP00000068201.2, ENSBTAT00000077467.2

    4. XM_024985431.2 → XP_024841199.2  voltage-dependent T-type calcium channel subunit alpha-1H isoform X4

      UniProtKB/TrEMBL
      F1MQV2
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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