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    POLR1B RNA polymerase I subunit B [ Bos taurus (domestic cattle) ]

    Gene ID: 282342, updated on 30-Jan-2025

    Summary

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    Official Symbol
    POLR1Bprovided by VGNC
    Official Full Name
    RNA polymerase I subunit Bprovided by VGNC
    Primary source
    VGNC:VGNC:33132
    See related
    BGD:BT26287; EnsemblRapid:ENSBTAG00070013520
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    RPOL-1l
    Orthologs
    human mouse all
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    Genomic context

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    See POLR1B in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (46252625..46274598)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112448781 Neighboring gene tubulin alpha-1B chain-like Neighboring gene tubulin tyrosine ligase Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 5 Neighboring gene large ribosomal subunit protein eL43-like Neighboring gene solute carrier family 20 member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase I activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribonucleoside binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase I subunit RPA2
    Names
    polymerase (RNA) I polypeptide B, 128kDa
    NP_001093762.1
    XP_059747008.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100292.1 → NP_001093762.1  DNA-directed RNA polymerase I subunit RPA2

      See identical proteins and their annotated locations for NP_001093762.1

      Status: PROVISIONAL

      Source sequence(s)
      BC148064
      UniProtKB/TrEMBL
      A0AAF6DM82, A6QLS0, F1MM94
      Related
      ENSBTAP00070018405.1, ENSBTAT00070030722.1
      Conserved Domains (3) summary
      cd00653
      Location:38 → 1133
      RNA_pol_B_RPB2; RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase ...
      pfam06883
      Location:563 → 616
      RNA_pol_Rpa2_4; RNA polymerase I, Rpa2 specific domain
      cl27130
      Location:186 → 375
      RNA_pol_Rpb2_1; RNA polymerase beta subunit

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46252625..46274598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891025.1 → XP_059747008.1  DNA-directed RNA polymerase I subunit RPA2 isoform X1

      UniProtKB/TrEMBL
      A0AAF6DM82
    Nucleotide Protein Strain
    Heading Accession and Version

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