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    PTGR2 prostaglandin reductase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 506263, updated on 30-Jan-2025

    Summary

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    Gene symbol
    PTGR2
    Gene description
    prostaglandin reductase 2
    See related
    BGD:BT29136; EnsemblRapid:ENSBTAG00070022955
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    ZADH1
    Orthologs
    human mouse all
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    Genomic context

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    See PTGR2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (85254444..85275898)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene mitotic deacetylase associated SANT domain protein Neighboring gene uncharacterized LOC132346417 Neighboring gene microRNA mir-7859 Neighboring gene zinc finger protein 410 Neighboring gene FAM161 centrosomal protein B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC134348

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in prostaglandin metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prostaglandin reductase 2
    Names
    15-oxoprostaglandin 13-reductase
    PRG-2
    zinc binding alcohol dehydrogenase, domain containing 1
    NP_001068717.1
    XP_005212001.1
    XP_015328711.1
    XP_015328712.1
    XP_059746251.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075249.2 → NP_001068717.1  prostaglandin reductase 2

      See identical proteins and their annotated locations for NP_001068717.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109688
      UniProtKB/Swiss-Prot
      Q32L99
      Related
      ENSBTAP00070031069.1, ENSBTAT00070051730.1
      Conserved Domains (2) summary
      cd08293
      Location:1 → 345
      PTGR2; Prostaglandin reductase
      COG2130
      Location:2 → 347
      CurA; NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      85254444..85275898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059890268.1 → XP_059746251.1  prostaglandin reductase 2 isoform X1

      UniProtKB/Swiss-Prot
      Q32L99

    2. XM_005211944.3 → XP_005212001.1  prostaglandin reductase 2 isoform X1

      See identical proteins and their annotated locations for XP_005212001.1

      UniProtKB/Swiss-Prot
      Q32L99
      Conserved Domains (2) summary
      cd08293
      Location:1 → 345
      PTGR2; Prostaglandin reductase
      COG2130
      Location:2 → 347
      CurA; NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]

    3. XM_015473225.3 → XP_015328711.1  prostaglandin reductase 2 isoform X1

      UniProtKB/Swiss-Prot
      Q32L99
      Conserved Domains (2) summary
      cd08293
      Location:1 → 345
      PTGR2; Prostaglandin reductase
      COG2130
      Location:2 → 347
      CurA; NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]

    4. XM_015473226.3 → XP_015328712.1  prostaglandin reductase 2 isoform X1

      UniProtKB/Swiss-Prot
      Q32L99
      Conserved Domains (2) summary
      cd08293
      Location:1 → 345
      PTGR2; Prostaglandin reductase
      COG2130
      Location:2 → 347
      CurA; NADPH-dependent curcumin reductase CurA [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32L99.1 GenPept UniProtKB/Swiss-Prot:Q32L99

    Gene LinkOut

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