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    Peg12 paternally expressed 12 [ Mus musculus (house mouse) ]

    Gene ID: 27412, updated on 9-Dec-2024

    Summary

    Official Symbol
    Peg12provided by MGI
    Official Full Name
    paternally expressed 12provided by MGI
    Primary source
    MGI:MGI:1351637
    See related
    Ensembl:ENSMUSG00000070526 AllianceGenome:MGI:1351637
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Frat3
    Summary
    Predicted to enable molecular function inhibitor activity. Acts upstream of or within embryonic axis specification. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including hemolymphoid system; liver; lung; nervous system; and placenta. Orthologous to human FRAT1 (FRAT regulator of WNT signaling pathway 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Peg12 in Genome Data Viewer
    Location:
    7 C; 7 34.38 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (62111619..62114258, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (62461871..62464510, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32061 Neighboring gene MAGE family member L2 Neighboring gene makorin, ring finger protein, 3 Neighboring gene STARR-seq mESC enhancer starr_18999 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_19000 Neighboring gene vomeronasal 2, receptor, pseudogene 61

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular function inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    paternally expressed 12
    Names
    frequently rearranged in advanced T-cell lymphomas 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013788.2NP_038816.1  paternally expressed 12

      See identical proteins and their annotated locations for NP_038816.1

      Status: VALIDATED

      Source sequence(s)
      AC027298
      Consensus CDS
      CCDS21328.1
      UniProtKB/TrEMBL
      Q9WVA7
      Related
      ENSMUSP00000091897.3, ENSMUST00000094339.3
      Conserved Domains (1) summary
      pfam05350
      Location:1232
      GSK-3_bind; Glycogen synthase kinase-3 binding

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      62111619..62114258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)