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    Arfrp1 ADP-ribosylation factor related protein 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31841, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Arfrp1provided by FlyBase
    Official Full Name
    ADP-ribosylation factor related protein 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0030088
    Locus tag
    Dmel_CG7039
    See related
    AllianceGenome:FB:FBgn0030088
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ARFRP1; ARP; Arp1; ARP1; CG7039; Dmel\CG7039; Q9W389
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in Golgi to plasma membrane protein transport; intracellular protein transport; and protein localization to Golgi apparatus. Predicted to be active in Golgi apparatus. Is expressed in adult head. Orthologous to human ARFRP1 (ARF related protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Arfrp1 in Genome Data Viewer
    Location:
    8C9-8C9; 1-26 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9107069..9108354)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9001102..9002387)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Bx42 Neighboring gene Adaptor Protein complex 1, gamma subunit Neighboring gene long non-coding RNA:CR45539

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication. Pasqualato S, et al. EMBO Rep, 2002 Nov. PMID 12429613, Free PMC Article
    2. The Drosophila Sec7 domain guanine nucleotide exchange factor protein Gartenzwerg localizes at the cis-Golgi and is essential for epithelial tube expansion. Armbruster K, et al. J Cell Sci, 2012 Mar 1. PMID 22349697
    3. The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2. Christis C, et al. J Cell Biol, 2012 Feb 6. PMID 22291037, Free PMC Article
    4. The ArfGAP Drongo Promotes Actomyosin Contractility during Collective Cell Migration by Releasing Myosin Phosphatase from the Trailing Edge. Zeledon C, et al. Cell Rep, 2019 Sep 17. PMID 31533044
    5. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins. Sinka R, et al. J Cell Biol, 2008 Nov 17. PMID 19001129, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ADP-ribosylation factor related protein 1
    Names
    Arfrp1-PA
    CG7039-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9107069..9108354
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132298.5 → NP_572526.1  ADP-ribosylation factor related protein 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572526.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RP3, Q9W389
      Related
      FBpp0071229
      Conserved Domains (2) summary
      cd04160
      Location:19 → 186
      Arfrp1; Arf-related protein 1 (Arfrp1)
      TIGR00231
      Location:17 → 181
      small_GTP; small GTP-binding protein domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W389 Q9W389

    Gene LinkOut

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