U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Mapmodulin mapmodulin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37043, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Mapmodulinprovided by FlyBase
    Official Full Name
    mapmodulinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034282
    Locus tag
    Dmel_CG5784
    See related
    AllianceGenome:FB:FBgn0034282
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe3A2; CG5784; CT18148; CT42180; Dmel\CG5784
    Summary
    Predicted to enable histone binding activity. Predicted to be involved in nucleocytoplasmic transport. Located in nucleoplasm. Is expressed in several structures, including adult brain cell body rind; central brain primordium; ganglia; gonad; and ventral nerve cord primordium. Used to study candidiasis. Orthologous to several human genes including ANP32A (acidic nuclear phosphoprotein 32 family member A); ANP32B (acidic nuclear phosphoprotein 32 family member B); and ANP32CP (acidic nuclear phosphoprotein 32 family member C, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Mapmodulin in Genome Data Viewer
    Location:
    54F4-54F4; 2-84 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17866178..17872015, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13753683..13759520, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene orai Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44417 Neighboring gene three rows Neighboring gene uncharacterized protein Neighboring gene Eag-like K[+] channel Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. An inducible nuclear body in the Drosophila germinal vesicle. Singer AB, et al. Nucleus, 2011 Sep-Oct. PMID 21941118, Free PMC Article
    2. Messenger RNA is a functional component of a chromatin insulator complex. Matzat LH, et al. EMBO Rep, 2013 Oct. PMID 23917615, Free PMC Article
    3. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
    4. Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1. Lou WP, et al. Front Mol Neurosci, 2017. PMID 29379413, Free PMC Article
    5. Direct Testing for Allele-Specific Expression Differences Between Conditions. León-Novelo L, et al. G3 (Bethesda), 2018 Feb 2. PMID 29167272, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleocytoplasmic transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    mapmodulin
    Names
    CG5784-PA
    CG5784-PB
    CG5784-PC
    CG5784-PD
    Mapmodulin-PA
    Mapmodulin-PB
    Mapmodulin-PC
    Mapmodulin-PD
    anon-fast-evolving-3A2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17866178..17872015 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079056.4 → NP_523780.1  mapmodulin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523780.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2VEM0, Q0E936, Q9V895
      UniProtKB/TrEMBL
      B7YZR7
      Related
      FBpp0086001
      Conserved Domains (3) summary
      sd00033
      Location:17 → 39
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:60 → 103
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:40 → 95
      LRR_8; Leucine rich repeat

    2. NM_166258.3 → NP_725732.1  mapmodulin, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725732.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2VEM0, Q0E936, Q9V895
      UniProtKB/TrEMBL
      B7YZR7
      Related
      FBpp0086002
      Conserved Domains (3) summary
      sd00033
      Location:17 → 39
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:60 → 103
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:40 → 95
      LRR_8; Leucine rich repeat

    3. NM_001169713.2 → NP_001163184.1  mapmodulin, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163184.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JGK5
      Conserved Domains (3) summary
      sd00033
      Location:17 → 39
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:60 → 103
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:40 → 95
      LRR_8; Leucine rich repeat

    4. NM_001103891.3 → NP_001097361.1  mapmodulin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097361.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JGK5
      Conserved Domains (3) summary
      sd00033
      Location:17 → 39
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:60 → 103
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:40 → 95
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7YZR7 B7YZR7
    E1JGK5 E1JGK5
    Q9V895.1 Q9V895

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous