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    Trf5 TBP-related factor 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33454, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Trf5provided by FlyBase
    Official Full Name
    TBP-related factor 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0031446
    Locus tag
    Dmel_CG15398
    See related
    AllianceGenome:FB:FBgn0031446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15398; Dmel\CG15398; trf5
    Summary
    Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to be involved in DNA-templated transcription initiation. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Trf5 in Genome Data Viewer
    Location:
    23A2-23A2; 2-7 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2695330..2696437, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2695330..2696437, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Gustatory receptor 23a Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 1 Neighboring gene uncharacterized protein Neighboring gene mir-4914 stem loop Neighboring gene Hepatocyte growth factor regulated tyrosine kinase substrate Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis. Laktionov PP, et al. Epigenetics Chromatin, 2018 Apr 2. PMID 29609617, Free PMC Article
    2. TRF4, the novel TBP-related protein of Drosophila melanogaster, is concentrated at the endoplasmic reticulum and copurifies with proteins participating in the processes associated with endoplasmic reticulum. Kurshakova MM, et al. J Cell Biochem, 2019 May. PMID 30426565
    3. Single-cell RNA sequencing identifies eggplant as a regulator of germ cell development in Drosophila. Sun Z, et al. EMBO Rep, 2023 Oct 9. PMID 37603128, Free PMC Article
    4. A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries. Slaidina M, et al. Genome Res, 2021 Oct. PMID 34389661, Free PMC Article
    5. The expression profile of purified Drosophila germline stem cells. Kai T, et al. Dev Biol, 2005 Jul 15. PMID 15927177

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TBP-related factor 5
    Names
    CG15398-PB
    Trf5-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2695330..2696437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134856.3 → NP_608700.2  TBP-related factor 5 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608700.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q058R9, Q9VQE8
      Conserved Domains (2) summary
      PLN00062
      Location:110 → 265
      PLN00062; TATA-box-binding protein; Provisional
      pfam00352
      Location:191 → 267
      TBP; Transcription factor TFIID (or TATA-binding protein, TBP)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQE8 Q9VQE8

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