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    Prr15l proline rich 15-like [ Mus musculus (house mouse) ]

    Gene ID: 217138, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Prr15lprovided by MGI
    Official Full Name
    proline rich 15-likeprovided by MGI
    Primary source
    MGI:MGI:2387599
    See related
    Ensembl:ENSMUSG00000047040 AllianceGenome:MGI:2387599
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Atad4; E230006A12Rik
    Summary
    Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human PRR15L (proline rich 15 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in colon adult (RPKM 63.3), large intestine adult (RPKM 44.2) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Prr15l in Genome Data Viewer
    Location:
    11 D; 11 60.16 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (96816987..96826474)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (96926161..96937833)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30571 Neighboring gene predicted gene, 38961 Neighboring gene VISTA enhancer mm1675 Neighboring gene CDK5 regulatory subunit associated protein 3 Neighboring gene STARR-positive B cell enhancer ABC_E202 Neighboring gene predicted gene 11525 Neighboring gene STARR-seq mESC enhancer starr_30572 Neighboring gene RIKEN cDNA D030028A08 gene Neighboring gene STARR-positive B cell enhancer ABC_E2367 Neighboring gene pyridoxine 5'-phosphate oxidase Neighboring gene Sp2 transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Clone Names

    • MGC37495

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 15-like protein
    Names
    ATPase family, AAA domain containing 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146026.2 → NP_666138.1  proline-rich protein 15-like protein

      See identical proteins and their annotated locations for NP_666138.1

      Status: VALIDATED

      Source sequence(s)
      AL596384
      Consensus CDS
      CCDS25307.1
      UniProtKB/Swiss-Prot
      Q8C307, Q8JZM2
      Related
      ENSMUSP00000103262.4, ENSMUST00000107636.4
      Conserved Domains (1) summary
      pfam15321
      Location:6 → 87
      ATAD4; ATPase family AAA domain containing 4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      96816987..96826474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245864.1 → XP_030101724.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      Q8C307, Q8JZM2
      Conserved Domains (1) summary
      pfam15321
      Location:6 → 87
      ATAD4; ATPase family AAA domain containing 4

    2. XM_030245865.2 → XP_030101725.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      Q8C307, Q8JZM2
      Related
      ENSMUSP00000103259.2, ENSMUST00000107633.2
      Conserved Domains (1) summary
      pfam15321
      Location:6 → 87
      ATAD4; ATPase family AAA domain containing 4

    3. XM_030245866.2 → XP_030101726.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      Q8C307, Q8JZM2
      Related
      ENSMUSP00000056614.6, ENSMUST00000054311.6
      Conserved Domains (1) summary
      pfam15321
      Location:6 → 87
      ATAD4; ATPase family AAA domain containing 4

    4. XM_030245863.2 → XP_030101723.1  proline-rich protein 15-like protein isoform X1

      UniProtKB/Swiss-Prot
      Q8C307, Q8JZM2
      Related
      ENSMUSP00000056647.6, ENSMUST00000062172.6
      Conserved Domains (1) summary
      pfam15321
      Location:6 → 87
      ATAD4; ATPase family AAA domain containing 4
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8JZM2.1 GenPept UniProtKB/Swiss-Prot:Q8JZM2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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