Dynlt1a dynein light chain Tctex-type 1A [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Dynlt1aprovided by MGI
Official Full Name: dynein light chain Tctex-type 1Aprovided by MGI
Primary source: MGI:MGI:3807506
See related: Ensembl:ENSMUSG00000092074 AllianceGenome:MGI:3807506
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: AGS2; Dynlt1; Tctel1; Tctex1; Tctex-1
Summary: Predicted to enable identical protein binding activity and transmembrane transporter binding activity. Predicted to be involved in several processes, including cardiac muscle cell apoptotic process; intracellular transport of viral protein in host cell; and neuron projection development. Predicted to be located in axonal growth cone; lamellipodium; and neuronal cell body. Predicted to be part of dynein complex. Orthologous to human DYNLT1 (dynein light chain Tctex-type 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Ubiquitous expression in testis adult (RPKM 116.9), CNS E18 (RPKM 51.4) and 27 other tissues See more
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Genomic context

Location:: 17 A1; 17 3.88 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (6356619..6367749, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (6306344..6317520, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

45.MMHAP76FRG12.seq (e-PCR)
- UniSTS:124592

M25825 (e-PCR)
- UniSTS:180956

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables molecular_function	ND No biological Data available more info
enables transmembrane transporter binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in axon development	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in cardiac muscle cell apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in dendrite development	ISO Inferred from Sequence Orthology more info
involved_in intracellular transport of viral protein in host cell	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of mitochondrial membrane permeability	ISO Inferred from Sequence Orthology more info
involved_in neuron projection morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of Rac protein signal transduction	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in regulation of cytoskeleton organization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in axonal growth cone	ISO Inferred from Sequence Orthology more info
part_of dynein complex	ISO Inferred from Sequence Orthology more info
located_in lamellipodium	ISO Inferred from Sequence Orthology more info
located_in neuronal cell body	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: dynein light chain Tctex-type 1A

Names: Activator of G-protein signaling 2; Dynein light chain Tctex-type 1; T-complex testis-specific protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.