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    UQCR-6.4 Ubiquinol-cytochrome c reductase 6.4 kDa subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36991, updated on 27-Dec-2024

    Summary

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    Official Symbol
    UQCR-6.4provided by FlyBase
    Official Full Name
    Ubiquinol-cytochrome c reductase 6.4 kDa subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034245
    Locus tag
    Dmel_CG14482
    See related
    AllianceGenome:FB:FBgn0034245
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14482; Dmel\CG14482; UCRY
    Summary
    Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex III. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including Malpighian tubule primordium; adult head; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and gut section. Orthologous to human UQCR11 (ubiquinol-cytochrome c reductase, complex III subunit XI). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See UQCR-6.4 in Genome Data Viewer
    Location:
    54C9-54C9; 2-83 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17572096..17572784, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13459601..13460289, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Nucleostemin 2 Neighboring gene Plenty of SH3s Neighboring gene uncharacterized protein Neighboring gene Rab4 Neighboring gene Dicer-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. Aspden JL, et al. Elife, 2014 Aug 21. PMID 25144939, Free PMC Article
    2. Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions. Yin S, et al. PLoS One, 2013. PMID 24069262, Free PMC Article
    3. The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis. Zhou F, et al. Metabolites, 2021 May 6. PMID 34066348, Free PMC Article
    4. Coordinated metabolic transitions during Drosophila embryogenesis and the onset of aerobic glycolysis. Tennessen JM, et al. G3 (Bethesda), 2014 Mar 12. PMID 24622332, Free PMC Article
    5. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Raja SJ, et al. Mol Cell, 2010 Jun 25. PMID 20620954

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of respiratory chain complex III ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquinol-cytochrome c reductase 6.4 kDa subunit
    Names
    CG14482-PA
    CG14482-PB
    UQCR-6.4-PA
    UQCR-6.4-PB
    Ubiquinol-cytochrome C reductase complex 6.4 kDa protein
    Ubiquinol-cytochrome c oxidoreductase 6.4 kDa
    Ubiquinol-cytochrome c reductase 6.4 kDa protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17572096..17572784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274128.2 → NP_001261057.1  Ubiquinol-cytochrome c reductase 6.4 kDa subunit, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261057.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q500Y7
      Conserved Domains (1) summary
      pfam08997
      Location:7 → 53
      UCR_6-4kD; Ubiquinol-cytochrome C reductase complex, 6.4kD protein

    2. NM_137389.4 → NP_611233.1  Ubiquinol-cytochrome c reductase 6.4 kDa subunit, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q500Y7
      Related
      FBpp0086062
      Conserved Domains (1) summary
      pfam08997
      Location:7 → 53
      UCR_6-4kD; Ubiquinol-cytochrome C reductase complex, 6.4kD protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q500Y7 Q500Y7

    Gene LinkOut

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