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    NimC2 Nimrod C2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34818, updated on 9-Dec-2024

    Summary

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    Official Symbol
    NimC2provided by FlyBase
    Official Full Name
    Nimrod C2provided by FlyBase
    Primary source
    FLYBASE:FBgn0028939
    Locus tag
    Dmel_CG18146
    See related
    AllianceGenome:FB:FBgn0028939
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS00180.14; CG18146; CG18146-PB; CT40902; Dmel\CG18146; DS00180.14; nimC2
    Summary
    Predicted to be involved in phagocytosis. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See NimC2 in Genome Data Viewer
    Location:
    34E5-34E5; 2-50 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13980126..13983269)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13980126..13983269)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Nimrod C1 Neighboring gene Cytochrome P450 28a5 Neighboring gene rickets Neighboring gene transfer RNA:Glutamine-CTG 4-1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GeneID in Drosophila. Parra G, et al. Genome Res, 2000 Apr. PMID 10779490, Free PMC Article
    2. Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Kocks C, et al. Cell, 2005 Oct 21. PMID 16239149
    3. Evolution of genes and repeats in the Nimrod superfamily. Somogyi K, et al. Mol Biol Evol, 2008 Nov. PMID 18703524
    4. Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells. Ulvila J, et al. J Biol Chem, 2006 May 19. PMID 16531407
    5. Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes. Kurucz E, et al. Curr Biol, 2007 Apr 3. PMID 17363253

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phagocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phagocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nimrod C2
    Names
    CG18146-PA
    CG18146-PB
    CG18146-PC
    NimC2-PA
    NimC2-PB
    NimC2-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13980126..13983269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298993.1 → NP_001285922.1  nimrod C2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285922.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V526, Q86BL2

    2. NM_176033.3 → NP_788047.1  nimrod C2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788047.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V526, Q86BL2
      Related
      FBpp0080166

    3. NM_135851.4 → NP_609695.2  nimrod C2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609695.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V526, Q9VJU4
      Related
      FBpp0080165
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86BL2 Q86BL2
    Q9VJU4 Q9VJU4

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