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    CG6356 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42893, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG6356provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039178
    Locus tag
    Dmel_CG6356
    See related
    AllianceGenome:FB:FBgn0039178
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6356; OCTN2; Slc22a16
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is expressed in adult head. Orthologous to human SLC22A6 (solute carrier family 22 member 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6356 in Genome Data Viewer
    Location:
    95F9-95F9; 3-84 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24283955..24288617)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20109677..20114339)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45662 Neighboring gene sheepish Neighboring gene uncharacterized protein Neighboring gene Uridine-cytidine kinase Neighboring gene uncharacterized protein Neighboring gene crumbs

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Reversible Carnitine Palmitoyltransferase 1 Inhibitor (Teglicar) Ameliorates the Neurodegenerative Phenotype in a Drosophila Huntington's Disease Model by Acting on the Expression of Carnitine-Related Genes. Bertapelle C, et al. Molecules, 2022 May 13. PMID 35630602, Free PMC Article
    2. Drosophila HisT is a specific histamine transporter that contributes to histamine recycling in glia. Xie J, et al. Sci Adv, 2022 Oct 28. PMID 36288320, Free PMC Article
    3. Severe Fertility Effects of sheepish Sperm Caused by Failure To Enter Female Sperm Storage Organs in Drosophila melanogaster. Tomaru M, et al. G3 (Bethesda), 2018 Jan 4. PMID 29158336, Free PMC Article
    4. L-Carnitine in Drosophila: A Review. Carillo MR, et al. Antioxidants (Basel), 2020 Dec 21. PMID 33371457, Free PMC Article
    5. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6356-PA
    organic cation transporter novel 2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24283955..24288617
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142983.3 → NP_651240.1  uncharacterized protein Dmel_CG6356 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651240.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MSK7, Q9VCA0
      Related
      FBpp0083985
      Conserved Domains (1) summary
      cd06174
      Location:167 → 544
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSK7 Q8MSK7
    Q9VCA0 Q9VCA0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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