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    Sugp2 SURP and G patch domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361126, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Sugp2provided by RGD
    Official Full Name
    SURP and G patch domain containing 2provided by RGD
    Primary source
    RGD:1306042
    See related
    EnsemblRapid:ENSRNOG00000020269 AllianceGenome:RGD:1306042
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sfrs14; Srsf14
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nuclear body. Predicted to be active in nucleoplasm. Orthologous to human SUGP2 (SURP and G-patch domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 102.9), Heart (RPKM 95.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sugp2 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19193910..19225364, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19159951..19191412, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (20908162..20939574, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene COPI coat complex subunit epsilon Neighboring gene DEAD-box helicase 49 Neighboring gene homer scaffold protein 3 Neighboring gene transmembrane protein 60-like Neighboring gene U6 spliceosomal RNA Neighboring gene armadillo repeat containing 6 Neighboring gene solute carrier family 25, member 42 Neighboring gene transmembrane protein 161A Neighboring gene myocyte enhancer factor 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    SURP and G-patch domain-containing protein 2
    Names
    serine/arginine-rich splicing factor 14
    splicing factor, arginine/serine-rich 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108397.1 → NP_001101867.1  SURP and G-patch domain-containing protein 2

      See identical proteins and their annotated locations for NP_001101867.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474031
      UniProtKB/TrEMBL
      A0A8I6A138, A6KA71, D3ZJH2
      Related
      ENSRNOP00000027457.4, ENSRNOT00000027457.6
      Conserved Domains (3) summary
      pfam01585
      Location:998 → 1041
      G-patch; G-patch domain
      pfam01805
      Location:769 → 819
      Surp; Surp module
      cl02715
      Location:571 → 619
      Surp; Surp module

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      19193910..19225364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275506.1 → XP_063131576.1  SURP and G-patch domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A138

    2. XM_063275503.1 → XP_063131573.1  SURP and G-patch domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A138, A6KA71, D3ZJH2

    3. XM_063275505.1 → XP_063131575.1  SURP and G-patch domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A138, A6KA71, D3ZJH2

    4. XM_063275504.1 → XP_063131574.1  SURP and G-patch domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A138, A6KA71, D3ZJH2

    RNA

    1. XR_010058302.1 RNA Sequence

    2. XR_010058298.1 RNA Sequence

    3. XR_010058301.1 RNA Sequence

    4. XR_010058300.1 RNA Sequence

    5. XR_010058299.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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