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    Tafa3 TAFA chemokine like family member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691123, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tafa3provided by RGD
    Official Full Name
    TAFA chemokine like family member 3provided by RGD
    Primary source
    RGD:1587462
    See related
    EnsemblRapid:ENSRNOG00000030253 AllianceGenome:RGD:1587462
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam19a3
    Summary
    Predicted to enable receptor ligand activity. Predicted to be involved in neuroblast differentiation; regulation of microglial cell activation; and regulation of neuroblast proliferation. Predicted to be active in extracellular space. Orthologous to human TAFA3 (TAFA chemokine like family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 37.0), Lung (RPKM 25.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tafa3 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (194952499..194968776, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (192264153..192280356, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (207249000..207258962, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350080 Neighboring gene uncharacterized LOC134485945 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1J Neighboring gene ras homolog family member C Neighboring gene Mov10 RNA helicase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables receptor ligand activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    chemokine-like protein TAFA-3
    Names
    family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
    family with sequence similarity 19 member A3, C-C motif chemokine like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      194952499..194968776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282742.1XP_063138812.1  chemokine-like protein TAFA-3 isoform X1

    2. XM_063282743.1XP_063138813.1  chemokine-like protein TAFA-3 isoform X2

      UniProtKB/TrEMBL
      A6K3P3, F1LXB8
      Related
      ENSRNOP00000046039.4, ENSRNOT00000040772.6
    3. XM_039103815.2XP_038959743.1  chemokine-like protein TAFA-3 isoform X2

      UniProtKB/TrEMBL
      A6K3P3, F1LXB8
      Related
      ENSRNOP00000107833.1, ENSRNOT00000172460.1
      Conserved Domains (1) summary
      pfam12020
      Location:43131
      TAFA; TAFA family
    4. XM_063282741.1XP_063138811.1  chemokine-like protein TAFA-3 isoform X1

      Related
      ENSRNOP00000110213.1, ENSRNOT00000124964.1

    RNA

    1. XR_005501179.2 RNA Sequence