Spaca3 sperm acrosome associated 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Spaca3provided by RGD
Official Full Name: sperm acrosome associated 3provided by RGD
Primary source: RGD:1306684
See related: EnsemblRapid:ENSRNOG00000006994 AllianceGenome:RGD:1306684
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Lyzc
Summary: Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to act upstream of or within sperm-egg recognition. Predicted to be located in acrosomal matrix and acrosomal membrane. Predicted to be active in acrosomal vesicle and sperm flagellum. Orthologous to human SPACA3 (sperm acrosome associated 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 215.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q26

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (66348336..66355808)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (65850618..65858090)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (68227736..68235295)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
NOT enables lysozyme activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in fusion of sperm to egg plasma membrane involved in single fertilization	IBA Inferred from Biological aspect of Ancestor more info
involved_in fusion of sperm to egg plasma membrane involved in single fertilization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within sperm-egg recognition	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in acrosomal matrix	ISO Inferred from Sequence Orthology more info
located_in acrosomal membrane	ISO Inferred from Sequence Orthology more info
is_active_in acrosomal vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in acrosomal vesicle	ISO Inferred from Sequence Orthology more info
located_in secretory granule	ISO Inferred from Sequence Orthology more info
is_active_in sperm flagellum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: sperm acrosome membrane-associated protein 3

Names: lysozyme c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.