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    Filip1l filamin A interacting protein 1-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304020, updated on 9-Dec-2024

    Summary

    Official Symbol
    Filip1lprovided by RGD
    Official Full Name
    filamin A interacting protein 1-likeprovided by RGD
    Primary source
    RGD:1565927
    See related
    EnsemblRapid:ENSRNOG00000001645 AllianceGenome:RGD:1565927
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565927
    Summary
    Predicted to be involved in protein localization to actin cytoskeleton. Predicted to be active in actin cytoskeleton. Orthologous to human FILIP1L (filamin A interacting protein 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 190.1), Heart (RPKM 159.1) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Filip1l in Genome Data Viewer
    Location:
    11q12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (56403467..56646422, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (42937353..43177085, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (45039488..45275141, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene collagen type VIII alpha 1 chain Neighboring gene cms1 ribosomal small subunit homolog Neighboring gene uncharacterized LOC134481062 Neighboring gene uncharacterized LOC134481063 Neighboring gene transmembrane protein 30C

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein localization to actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    filamin A-interacting protein 1-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427234.1NP_001414163.1  filamin A-interacting protein 1-like

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      D4A900
      Related
      ENSRNOP00000045927.4, ENSRNOT00000046383.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      56403467..56646422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017598112.3XP_017453601.2  filamin A-interacting protein 1-like isoform X1

      UniProtKB/TrEMBL
      D4A900
    2. XM_063270563.1XP_063126633.1  filamin A-interacting protein 1-like isoform X3

      UniProtKB/TrEMBL
      A6IQM5
    3. XM_063270564.1XP_063126634.1  filamin A-interacting protein 1-like isoform X3

      UniProtKB/TrEMBL
      A6IQM5
    4. XM_039088830.2XP_038944758.1  filamin A-interacting protein 1-like isoform X2

      UniProtKB/TrEMBL
      D4A900
      Conserved Domains (2) summary
      COG1196
      Location:227811
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09727
      Location:64284
      CortBP2; Cortactin-binding protein-2