U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Gosr2 golgi SNAP receptor complex member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64154, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gosr2provided by RGD
    Official Full Name
    golgi SNAP receptor complex member 2provided by RGD
    Primary source
    RGD:62079
    See related
    EnsemblRapid:ENSRNOG00000003506 AllianceGenome:RGD:62079
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intra-Golgi vesicle-mediated transport and vesicle fusion. Predicted to act upstream of or within vesicle-mediated transport. Part of SNARE complex. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 6. Orthologous to human GOSR2 (golgi SNAP receptor complex member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 363.4), Testes (RPKM 172.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gosr2 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (89085323..89105665, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (88585291..88605642, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (91735772..91756123, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103693460 Neighboring gene lysozyme-like 6 Neighboring gene reprimo-like Neighboring gene mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 Neighboring gene uncharacterized LOC120095298 Neighboring gene Wnt family member 9B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables SNAP receptor activity  
    enables SNAP receptor activity  
    enables SNARE binding  
    Process Evidence Code Pubs
    NOT involved_in endoplasmic reticulum to Golgi vesicle-mediated transport  
    involved_in intra-Golgi vesicle-mediated transport  
    involved_in intra-Golgi vesicle-mediated transport  
    involved_in intra-Golgi vesicle-mediated transport  
    involved_in membrane fusion  
    involved_in protein transport  
    involved_in vesicle fusion  
    involved_in vesicle-mediated transport  
    acts_upstream_of_or_within vesicle-mediated transport  
    Component Evidence Code Pubs
    is_active_in ER to Golgi transport vesicle membrane  
    is_active_in Golgi apparatus  
    located_in Golgi apparatus  
    located_in Golgi apparatus  
    located_in Golgi membrane  
    located_in Golgi membrane  
    part_of SNARE complex  
    part_of SNARE complex PubMed 
    located_in cytosol  
    located_in cytosol  
    is_active_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane  
    is_active_in late endosome membrane  
    located_in membrane  
    located_in nucleoplasm  
    located_in nucleoplasm  

    General protein information

    Preferred Names
    Golgi SNAP receptor complex member 2
    Names
    27 kDa Golgi SNARE protein
    membrin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031685.2NP_113873.1  Golgi SNAP receptor complex member 2

      See identical proteins and their annotated locations for NP_113873.1

      Status: PROVISIONAL

      Source sequence(s)
      BC061994
      UniProtKB/Swiss-Prot
      O08566, O35165, Q6GSW2
      UniProtKB/TrEMBL
      A0A8L2Q181, A6HJS5
      Related
      ENSRNOP00000005046.5, ENSRNOT00000005046.6
      Conserved Domains (1) summary
      cd15863
      Location:120185
      SNARE_GS27; SNARE motif of GS27

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      89085323..89105665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597520.2XP_017453009.1  Golgi SNAP receptor complex member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AG32, A6HJS4
      Related
      ENSRNOP00000084049.2, ENSRNOT00000114651.2
      Conserved Domains (1) summary
      cl22856
      Location:113138
      SNARE; SNARE motif
    External link. Please review our privacy policy.