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    Tesl1 testin LIM domain protein like 1 [ Mus musculus (house mouse) ]

    Gene ID: 236749, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tesl1provided by MGI
    Official Full Name
    testin LIM domain protein like 1provided by MGI
    Primary source
    MGI:MGI:3648288
    See related
    Ensembl:ENSMUSG00000068113 AllianceGenome:MGI:3648288
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm4907; EG236749
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of cell population proliferation. Predicted to be located in cytosol; focal adhesion; and plasma membrane. Predicted to be part of protein-containing complex. Orthologous to human TES (testin LIM domain protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 5.3) and large intestine adult (RPKM 0.2) See more
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    Genomic context

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    See Tesl1 in Genome Data Viewer
    Location:
    X A2; X 17.42 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (23710943..23773850)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (23882524..23907608)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene kelch-like 13 Neighboring gene STARR-seq mESC enhancer starr_46924 Neighboring gene STARR-seq mESC enhancer starr_46925 Neighboring gene STARR-seq mESC enhancer starr_46926 Neighboring gene cyclin-dependent kinase 2 interacting protein pseudogene Neighboring gene WD repeat domain 44 Neighboring gene STARR-seq mESC enhancer starr_46927 Neighboring gene STARR-seq mESC enhancer starr_46928 Neighboring gene testis derived transcript pseudogene Neighboring gene STARR-seq mESC enhancer starr_46929 Neighboring gene testin LIM domain protein like 2 Neighboring gene STARR-seq mESC enhancer starr_46930 Neighboring gene STARR-seq mESC enhancer starr_46931 Neighboring gene STARR-seq mESC enhancer starr_46932 Neighboring gene STARR-seq mESC enhancer starr_46933 Neighboring gene STARR-seq mESC enhancer starr_46934 Neighboring gene STARR-seq mESC enhancer starr_46935 Neighboring gene X-linked lymphocyte-regulated protein PM1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    Tes-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034864.4 → NP_001030036.2  Tes-like protein

      See identical proteins and their annotated locations for NP_001030036.2

      Status: VALIDATED

      Source sequence(s)
      AL807248
      Consensus CDS
      CCDS53019.1
      UniProtKB/TrEMBL
      B1AXB9, Q3V085
      Related
      ENSMUSP00000112313.3, ENSMUST00000116614.3
      Conserved Domains (4) summary
      cd09413
      Location:226 → 283
      LIM1_Testin; The first LIM domain of Testin
      cd09416
      Location:289 → 344
      LIM2_Testin; The second LIM domain of Testin
      cd09419
      Location:351 → 409
      LIM3_Testin; The third LIM domain of Testin
      cd09829
      Location:101 → 188
      PET_testin; The PET domain of Testin

    2. NM_001418376.1 → NP_001405305.1  Tes-like protein

      Status: VALIDATED

      Source sequence(s)
      AL807248
      UniProtKB/TrEMBL
      B1AXB9
      Related
      ENSMUSP00000136747.2, ENSMUST00000163718.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      23710943..23773850
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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