Cyp2t4 cytochrome P450, family 2, subfamily t, polypeptide 4 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cyp2t4provided by MGI
Official Full Name: cytochrome P450, family 2, subfamily t, polypeptide 4provided by MGI
Primary source: MGI:MGI:2686296
See related: Ensembl:ENSMUSG00000078787 AllianceGenome:MGI:2686296
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1448; Gm1450
Summary: Predicted to enable arachidonate epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in epoxygenase P450 pathway and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Orthologous to human CYP2T1P (cytochrome P450 family 2 subfamily T member 1, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 7 A3; 7 15.83 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (26853139..26857989)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (27153714..27158564)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH125240 (e-PCR)
- UniSTS:162062

Ier4 (e-PCR), detects polymorphism
- UniSTS:143451

Ier4 (e-PCR), detects polymorphism
- UniSTS:143452

RH127214 (e-PCR)
- UniSTS:208091

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables arachidonate epoxygenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables heme binding	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in epoxygenase P450 pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in xenobiotic metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome P450, family 2, subfamily t, polypeptide 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100184.1 → NP_001093654.1 cytochrome P450, family 2, subfamily t, polypeptide 4

Status: PROVISIONAL

Source sequence(s)

AC157553

Consensus CDS

CCDS52157.1

UniProtKB/TrEMBL

D3Z7F6, E9PWV0

Related

ENSMUSP00000126779.2, ENSMUST00000164093.8

Conserved Domains (1) summary

pfam00067
Location:63 → 498

p450; Cytochrome P450