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    nagZ beta-hexosaminidase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880216, updated on 24-Aug-2024

    Summary

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    Gene symbol
    nagZ
    Gene description
    beta-hexosaminidase
    Locus tag
    PA3005
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3365756..3366754, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene S-methyl-5'-thioinosine phosphorylase Neighboring gene transcriptional regulator PsrA Neighboring gene LexA repressor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NagZ inactivation prevents and reverts beta-lactam resistance, driven by AmpD and PBP 4 mutations, in Pseudomonas aeruginosa. Zamorano L, et al. Antimicrob Agents Chemother, 2010 Sep. PMID 20566764, Free PMC Article
    2. Molecular characterization of the beta-N-acetylglucosaminidase of Escherichia coli and its role in cell wall recycling. Cheng Q, et al. J Bacteriol, 2000 Sep. PMID 10940025, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that the inactivation of nagZ dramatically reduces the capacity of P. aeruginosa to develop ceftazidime resistance
      Title: NagZ inactivation prevents and reverts beta-lactam resistance, driven by AmpD and PBP 4 mutations, in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell wall macromolecule catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-hexosaminidase
    NP_251695.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3365756..3366754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251695.1 beta-hexosaminidase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251695.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5EDQ6
      Conserved Domains (1) summary
      PRK05337
      Location:2 → 329
      PRK05337; beta-hexosaminidase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HZK0.1

    Gene LinkOut

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